The Influence of Plasma Prekallikrein Oligonucleotide Antisense Therapy on Coagulation and Fibrinolysis Assays: A Post-hoc Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Thrombosis and Haemostasis"
DOI: 10.1055/a-1926-2367
Abstract: Background Congenital prekallikrein deficiency has been associated with increased risk of thrombosis in a few uncontrolled studies. Prekallikrein levels were reduced by 36-94% (median 75%) in a phase 2 study with the prekallikrein specific antisense… read more here.
Keywords: plasma prekallikrein; coagulation fibrinolysis; activity;
Visualization of Domain- and Concentration-Dependent Impact of Thrombomodulin on Differential Regulation of Coagulation and Fibrinolysis
Sign Up to like & getrecommendations! Published in 2022 at "Thrombosis and Haemostasis"
DOI: 10.1055/s-0042-1757407
Abstract: Background Thrombomodulin (TM) functions as a dual modulator—anticoagulant and antifibrinolytic potential—by the thrombin-dependent activation of protein C and thrombin-activatable fibrinolysis inhibitor (TAFI). Activated TAFI cleaves the C-terminal lysine of partially degraded fibrin and inhibits both… read more here.
Keywords: fibrinolysis; domain concentration; coagulation fibrinolysis; concentration dependent ... See more keywords
Correlation between Coagulation Fibrinolysis Function and Outcomes during Hospitalization in Patients with Severe Traumatic Hemorrhagic Shock
Sign Up to like & getrecommendations! Published in 2022 at "Emergency Medicine International"
DOI: 10.1155/2022/3775868
Abstract: Objective To analyze the correlation between coagulation fibrinolysis function and outcomes during hospitalization in patients with severe traumatic hemorrhagic shock. Methods A retrospective collection was performed on the clinical data of 106 patients with severe… read more here.
Keywords: coagulation; patients severe; severe traumatic; group ... See more keywords
Coagulation and Fibrinolysis Imbalance Demonstrated By Novel Simultaneous Thrombin and Plasmin Generation Assay during L-Asparaginase Treatment Phase of Induction Therapy in Pediatric Acute Lymphoblastic Leukemia
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-110411
Abstract: Introduction: L-asparaginase (L-Asp) is one of the risk factor of thromboembolism during ALL chemotherapy. Although the pathogenesis has been still unclarified, L-Asp may have profound effects on hepatic synthesis of pro-, anti-coagulant and fibrinolytic factors.… read more here.
Keywords: phase; coagulation; plasmin; coagulation fibrinolysis ... See more keywords
Coagulation and fibrinolysis in hyperparathyroidism secondary to vitamin D deficiency
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine Connections"
DOI: 10.1530/ec-17-0249
Abstract: Introduction Abnormal coagulation tests have been observed in patients with primary hyperparathyroidism (HPT) suggesting a prothrombotic effect of parathyroid hormone (PTH). Vitamin D deficiency (VIDD) is the most frequent cause of secondary HPT. Aim of… read more here.
Keywords: vidd; vitamin; hpt; coagulation fibrinolysis ... See more keywords
The significance of coagulation and fibrinolysis-related parameters in predicting postoperative venous thrombosis in patients with breast cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Gland surgery"
DOI: 10.21037/gs-21-117
Abstract: Background To explore the expression level of coagulation and fibrinolysis-related indexes in the plasma of breast cancer patients after surgery, and explore their predictive value for deep venous thrombosis (DVT). Methods From May 2016 to… read more here.
Keywords: coagulation; venous thrombosis; breast cancer; coagulation fibrinolysis ... See more keywords
Infectious agents including COVID-19 and the involvement of blood coagulation and fibrinolysis. A narrative review.
Sign Up to like & getrecommendations! Published in 2021 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202105_25956
Abstract: OBJECTIVE Platelets, blood coagulation along with fibrinolysis are greatly involved in the pathophysiology of infectious diseases induced by bacteria, parasites and virus. This phenomenon is not surprising since both the innate immunity and the hemostatic… read more here.
Keywords: infectious agents; blood coagulation; coagulation fibrinolysis; fibrinolysis ... See more keywords
Imbalance in Coagulation/Fibrinolysis Inhibitors Resulting in Extravascular Thrombin Generation in Gliomas of Varying Levels of Malignancy
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11050663
Abstract: Neoplastic processes are integrally related to disturbances in the mechanisms regulating hemostatic processes. Brain tumors, including gliomas, are neoplasms associated with a significantly increased risk of thromboembolic complications, affecting 20–30% of patients. As gliomas proliferate,… read more here.
Keywords: coagulation; gliomas varying; gliomas; grade gliomas ... See more keywords