A comprehensive analysis of coagulopathy during anti-B cell maturation antigen chimeric antigen receptor-T therapy in multiple myeloma, a retrospective study based on LEGEND-2.
Sign Up to like & getrecommendations! Published in 2023 at "Hematological oncology"
DOI: 10.1002/hon.3155
Abstract: Chimeric antigen receptor (CAR)-reprogrammed T cell therapy is a novel and powerful treatment against hematological malignancies. Cytokine release syndrome (CRS) and other potentially life-threatening toxicities are known side effects which need appropriate management and supportive… read more here.
Keywords: cell; coagulopathy; therapy; chimeric antigen ... See more keywords
Venous and arterial thromboembolic disease in COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-021-02524-1
Abstract: The severe acute respiratory syndrome (SARS) CoV-2 (the virus that causes COVID‐19) infection has led to a pandemic of unprecedented scale. Its disease consequences have to be adequately addressed to prevent further morbidity and mortality.… read more here.
Keywords: covid patients; venous arterial; disease; covid ... See more keywords
Repeated intracranial hemorrhage after delivery induced by coagulopathy associated with multiple venous malformations - Case report.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.05.089
Abstract: Background Venous malformations are classified as slow-flow vascular malformations. Coagulation abnormalities are known to be frequent among patients with venous malformations. We report a case of repeated intracranial hemorrhage after delivery, induced by coagulopathy associated… read more here.
Keywords: repeated intracranial; delivery; case; multiple venous ... See more keywords
Case report: An HIV+ patient presenting with pancytopenia, hepatic failure, and coagulopathy; a rare small cell liver carcinoma with diffuse splenic and bone marrow metastasis diagnosed at autopsy.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2017.09.002
Abstract: A 34-year old male with a giant condyloma acuminatum of the anus secondary to HIV infection presented to the emergency department with a persistent nose bleed lasting 2-3days, acute anemia, thrombocytopenia, and coagulopathy. The patient… read more here.
Keywords: coagulopathy; small cell; bone marrow;
Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients
Sign Up to like & getrecommendations! Published in 2020 at "Thrombosis and Haemostasis"
DOI: 10.1055/s-0040-1715835
Abstract: The ongoing COVID-19 pandemic has caused significant morbidity and mortality worldwide, as well as profound effects on society. COVID-19 patients have an increased risk of thromboembolic (TE) complications, which develop despite pharmacological thromboprophylaxis. The mechanism… read more here.
Keywords: covid patients; critically ill; ill covid; coagulopathy ... See more keywords
TRAUMA-DERIVED EXTRACELLULAR VESICLES ARE SUFFICIENT TO INDUCE ENDOTHELIAL DYSFUNCTION AND COAGULOPATHY
Sign Up to like & getrecommendations! Published in 2022 at "Shock"
DOI: 10.1097/shk.0000000000001950
Abstract: ABSTRACT—Introduction Although a number of studies have demonstrated increased release of extracellular vesicles (EVs) and changes in their origin differentials after trauma, the biologic significance of EVs is not well understood. We hypothesized that EVs… read more here.
Keywords: extracellular vesicles; trauma; coagulopathy; injured patients ... See more keywords
A prospective observational study of acute traumatic coagulopathy in traumatic bleeding from the battlefield
Sign Up to like & getrecommendations! Published in 2020 at "Transfusion"
DOI: 10.1111/trf.15658
Abstract: Acute trauma coagulopathy (ATC) after military trauma has not been comprehensively studied. ATC is defined as a prolonged prothrombin time ratio (PTr) or reduced clot amplitude (A5) in viscoelastic testing. Compared to civilian trauma, military… read more here.
Keywords: observational study; prospective observational; traumatic coagulopathy; trauma ... See more keywords
COVID-19 and its implications for thrombosis and anticoagulation
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood.2020006000
Abstract: Abstract Severe acute respiratory syndrome coronavirus 2, coronavirus disease 2019 (COVID-19)-induced infection can be associated with a coagulopathy, findings consistent with infection-induced inflammatory changes as observed in patients with disseminated intravascular coagulopathy (DIC). The lack… read more here.
Keywords: anticoagulation; implications thrombosis; associated coagulopathy; covid ... See more keywords
Coagulopathy associated with COVID-19 – Perspectives & Preventive strategies using a biological response modifier Glucan
Sign Up to like & getrecommendations! Published in 2020 at "Thrombosis Journal"
DOI: 10.1186/s12959-020-00239-6
Abstract: Direct endothelial injury by viruses and dysregulation of clotting mechanisms due to cytokine storm are the major precipitating factors of mortality in COVID-19; both are attributed to a fundamental dysregulation of the immune system. While… read more here.
Keywords: coagulopathy; biological response; response modifier; mortality ... See more keywords