Targeting the R domain of coagulase by active vaccination protects mice against lethal Staphylococcus aureus infection.
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DOI: 10.1016/j.micinf.2018.11.001
Abstract: Coagulase (Coa) secreted by Staphylococcus aureus is associated with the establishment of staphylococcal disease, which activates host prothrombin and generates fibrin shields. The R domain of Coa, consisting of several conserved repeats, is important in… read more here.
Keywords: aureus infection; staphylococcus aureus; coar6; coagulase ... See more keywords