An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Sign Up to like & getrecommendations! Published in 2022 at "Communications Biology"
DOI: 10.1038/s42003-022-03063-y
Abstract: β-Coronaviruses such as SARS-CoV-2 hijack coatomer protein-I (COPI) for spike protein retrograde trafficking to the progeny assembly site in endoplasmic reticulum-Golgi intermediate compartment (ERGIC). However, limited residue-level details are available into how the spike interacts… read more here.
Keywords: coatomer; copi; retrograde trafficking; sars cov ... See more keywords
Coatomer in the universe of cellular complexity
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e19-01-0012
Abstract: Eukaryotic cells possess considerable internal complexity, differentiating them from prokaryotes. Eukaryogenesis, an evolutionary transitional period culminating in the last eukaryotic common ancestor (LECA), marked the origin of the eukaryotic endomembrane system. LECA is reconstructed as… read more here.
Keywords: bar; coatomer universe; cellular complexity; coatomer ... See more keywords