Cobalamin‐Dependent Aryl Methyl Ether O‐Demethylases: Promising Enzymes for Biocatalytic Applications from Lignin Valorization to Organic Synthesis
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DOI: 10.1002/cctc.202500877
Abstract: Cobalamin‐dependent aryl methyl ether O‐demethylase is a multi‐component enzyme system that converts O‐methylated aromatic compounds into demethylated phenolics. The central enzyme of the system is a cobalamin‐dependent protein that interacts with methyltransferase enzymes for transferring… read more here.
Keywords: cobalamin dependent; aryl methyl; methyl ether; dependent aryl ... See more keywords
Computational Study of Cobalamin-Dependent Epoxyqueuosine Reductase: Formation of a Key Organometallic Intermediate with a "Stable-Yet-Fragile" Co-C Bond.
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DOI: 10.1021/acs.inorgchem.5c01837
Abstract: QueG is a cobalamin-dependent enzyme that catalyzes the epoxide reduction of queuosine (Q). The quantum chemical cluster approach has been performed to investigate the mechanism of the QueG-catalyzed reaction. Our calculations reveal a nucleophilic attack… read more here.
Keywords: yet fragile; cobalamin dependent; stable yet; fragile bond ... See more keywords