Heterogeneous Cobalt‐Catalyzed Direct N‐Formylation of Isoquinolines with CO2 and H2
Sign Up to like & getrecommendations! Published in 2017 at "ChemCatChem"
DOI: 10.1002/cctc.201601682
Abstract: Isoquinolines (IQs) are an abundant feedstock, and N‐formyl‐1,2,3,4‐tetrahydroisoquinolines (FTHIQs) are valuable fine chemicals and key intermediates. Herein, we report for the first time the Co0/ZnCl2‐catalyzed direct N‐formylation of IQs by using CO2 with H2 to… read more here.
Keywords: formylation; formylation isoquinolines; heterogeneous cobalt; cobalt catalyzed ... See more keywords
Heterogeneous Cobalt‐Catalyzed C−C Bond Cleavage in Alcohols to Carbonyl Compounds
Sign Up to like & getrecommendations! Published in 2021 at "ChemCatChem"
DOI: 10.1002/cctc.202100950
Abstract: Cobalt oxide hydrate (Co(OH)x) supported on metal oxides were prepared. The oxidative cleavage of C(OH)−C bond in alcohol was catalyzed by Co(OH)x/metal oxides using molecular oxygen as the oxidant, and the corresponding product was obtained… read more here.
Keywords: cleavage; bond; heterogeneous cobalt; cobalt catalyzed ... See more keywords
Cobalt-Catalyzed Oxidative C-H Activation: Strategies and Concepts.
Sign Up to like & getrecommendations! Published in 2020 at "ChemSusChem"
DOI: 10.1002/cssc.202000024
Abstract: Inexpensive cobalt-catalyzed oxidative C-H functionalization has emerged as a powerful tool for the construction of C-C and C-Het bonds, which offers unique potential for transformative applications to modern organic synthesis. In the early stage, these… read more here.
Keywords: activation strategies; oxidative activation; catalyzed oxidative; cobalt catalyzed ... See more keywords
Cobalt-Catalyzed Highly Regioselective Three-Component Arylcarboxylation of Acrylate with Aryl Bromides and Carbon Dioxide.
Sign Up to like & getrecommendations! Published in 2021 at "ChemSusChem"
DOI: 10.1002/cssc.202101963
Abstract: Cobalt-catalyzed regioselective three-component arylcarboxylation of acrylate with aryl bromides and carbon dioxide (CO2) has been developed. The reaction is carried out using cobalt chloride as a pre-catalyst and zinc powder as a reducing reagent under… read more here.
Keywords: regioselective three; aryl bromides; cobalt; arylcarboxylation ... See more keywords
Cobalt-catalyzed oxidative esterification of allylic/benzylic C(sp3)–H bonds
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.04.002
Abstract: A protocol for the cobalt-catalyzed oxidative esterification of allylic/benzylic C(sp3)–H bonds with carboxylic acids was developed in this work. Mechanistic studies revealed that C(sp3)–H bond activation in the hydrocarbon was the turnover-limiting step and the… read more here.
Keywords: esterification allylic; benzylic sp3; cobalt catalyzed; oxidative esterification ... See more keywords
Cobalt-catalyzed C H activation/C O formation: Synthesis of benzofuranones
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.151396
Abstract: Abstract Herein, C H activation/C O formation reaction using novel cobalt catalytic system is reported. This reaction was given benzofuranones in moderate to excellent yields at room-temperature under air reaction conditions. The introduced strategy is… read more here.
Keywords: formation synthesis; cobalt catalyzed; catalyzed activation; activation ... See more keywords
Cobalt-Catalyzed Cross-Couplings between Alkyl Halides and Grignard Reagents.
Sign Up to like & getrecommendations! Published in 2020 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.0c00238
Abstract: ConspectusMetal-catalyzed cross-couplings have emerged as essential tools for the construction of C-C bonds. The identification of efficient catalytic systems as well as large substrate scope made these cross-couplings key reactions to access valuable molecules ranging… read more here.
Keywords: cross couplings; alkyl halides; grignard reagents; cobalt catalyzed ... See more keywords
Cobalt-Catalyzed Ligand-Controlled Divergent Regioselective Reactions of 1,6-Enynes with Thiols
Sign Up to like & getrecommendations! Published in 2020 at "Organometallics"
DOI: 10.1021/acs.organomet.0c00179
Abstract: An efficient cobalt-catalyzed method for the synthesis of carbocyclic organosulfur compounds from 1,6-enynes and thiols has been developed. The significance of this methodology is the ability to gi... read more here.
Keywords: divergent regioselective; controlled divergent; enynes thiols; cobalt catalyzed ... See more keywords
A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)–C(sp2) Cross-Coupling with Chiral Multidentate N,N,P-Ligand
Sign Up to like & getrecommendations! Published in 2021 at "Organometallics"
DOI: 10.1021/acs.organomet.1c00190
Abstract: A cobalt-catalyzed enantioconvergent radical Negishi C(sp)−C(sp) cross-coupling of racemic benzyl chlorides with arylzinc reagents has been developed in good yield with moderate enantioselectivities. This strategy provides an expedient access toward a range of enantioenriched 1,1-diarylmethanes.… read more here.
Keywords: enantioconvergent cross; cross coupling; cross; catalyzed enantioconvergent ... See more keywords
Cobalt-Catalyzed Acceptorless Dehydrogenation of Alcohols to Carboxylate Salts and Hydrogen.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c00193
Abstract: The facile oxidation of alcohols to carboxylate salts and H2 is achieved using a simple and readily accessible cobalt pincer catalyst (NNNHtBuCoBr2). The reaction follows an acceptorless dehydrogenation pathway and displays good functional group tolerance.… read more here.
Keywords: alcohols carboxylate; dehydrogenation; carboxylate salts; cobalt catalyzed ... See more keywords
Cobalt-Catalyzed Direct C-H Carbonylative Synthesis of Free (NH)-Indolo[1,2-a]quinoxalin-6(5H)-ones.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c03900
Abstract: A cobalt-catalyzed direct C-H carbonylative reaction of N-(2-(1H-indol-1-yl)phenyl)picolinamides for the synthesis of (NH)-indolo[1,2-a]quinoxalin-6(5H)-one skeletons has been developed. Using benzene-1,3,5-triyl triformate (TFBen) as the CO source and picolinamide as the traceless directing group, various free (NH)-indolo[1,2-a]quinoxalin-6(5H)-ones… read more here.
Keywords: indolo quinoxalin; free indolo; cobalt catalyzed; catalyzed direct ... See more keywords