Direct Cobamide Remodeling via Additional Function of Cobamide Biosynthesis Protein CobS from Vibrio cholerae
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DOI: 10.1128/jb.00172-21
Abstract: Cobamides are widespread cofactors that mediate metabolic interactions in complex microbial communities. Few studies directly examine cobamide profiles, but several have shown that mammalian gastrointestinal tracts are rich in cobamide analogs. ABSTRACT Vitamin B12 belongs… read more here.
Keywords: cobamide; cobamide profiles; cobs; cobamide biosynthesis ... See more keywords
Identification of a Novel Cobamide Remodeling Enzyme in the Beneficial Human Gut Bacterium Akkermansia muciniphila
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DOI: 10.1128/mbio.02507-20
Abstract: Cobamides, comprising the vitamin B12 family of cobalt-containing cofactors, are required for metabolism in all domains of life, including most bacteria. Cobamides have structural variability in the lower ligand, and selectivity for particular cobamides has… read more here.
Keywords: human gut; cobamide; gut bacterium; muciniphila ... See more keywords