Randomized Trial Evaluating the Neurotoxicity of Dolutegravir/Abacavir/Lamivudine and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide: GESIDA 9016
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DOI: 10.1093/ofid/ofaa482
Abstract: Abstract Background Despite evidence shown of dolutegravir (DTG)-related neurotoxicity, which may be more common when combined with abacavir (ABC), its reversibility has not been explored in a clinical trial. Methods We conducted a randomized, multicenter,… read more here.
Keywords: ftc taf; cobi ftc; neuropsychiatric symptoms; evg cobi ... See more keywords
Virological Outcomes of EVG/COBI/FTC/TDF and EVG/COBI/FTC/TAF in Antiretroviral-Naive HIV-1-Infected Participants with Baseline HIV-1 RNA ≥1,000,000 Copies/ml: A Post Hoc Analysis of Phase III Clinical Trials
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DOI: 10.3851/imp3187
Abstract: We address a data gap identified by Adams et al. [1], of virological efficacy outcomes and emergent drug resistance in HIV-1-infected, antiretroviral treatment (ART)naive participants with baseline (BL) viral loads (VL) >1,000,000 copies/ml. Initial ART… read more here.
Keywords: ftc; ftc tdf; evg cobi; cobi ftc ... See more keywords