Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Sign Up to like & getrecommendations! Published in 2019 at "Nature Medicine"
DOI: 10.1038/s41591-019-0474-7
Abstract: Melanoma treatment has progressed in the past decade with the development and approval of immune checkpoint inhibitors targeting programmed death 1 (PD-1) or its ligand (PD-L1) and cytotoxic T lymphocyte-associated antigen 4, as well as… read more here.
Keywords: cobimetinib vemurafenib; braf mek; vemurafenib braf; braf ... See more keywords
Atezolizumab (A) + cobimetinib (C) + vemurafenib (V) in BRAFV600-mutant metastatic melanoma (mel): Updated safety and clinical activity.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.3063
Abstract: 3063Background: Targeted inhibition of MEK with C and BRAF with V in BRAFV600-mutant mel can lead to both anticancer immune activation and direct tumor cell death. A, an anti–PD-L1 monoclonal antib... read more here.
Keywords: cobimetinib vemurafenib; atezolizumab cobimetinib; vemurafenib brafv600; mutant metastatic ... See more keywords