Articles with "cobll1" as a keyword



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Mir-424 and Mir-503 Regulates Cobll1 Expression during the CML Progression

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Published in 2017 at "Blood"

DOI: 10.1182/blood.v130.suppl_1.4177.4177

Abstract: Up- or down-regulation of many miRNAs plays an important role in chronic myeloid leukemia (CML), however underlying mechanisms remain to be elucidated. Here, we report miRNA-424 and miR-503 regulates Cobll1 expression during CML progression. In… read more here.

Keywords: mir 424; mir 503; mir; cobll1 ... See more keywords
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Cobll1: A new player in CML

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.21705

Abstract: Chronic myeloid leukemia (CML) is a malignant cancer derived from hematopoietic stem cells. CML is induced by an oncogenic BCR-ABL1 fusion protein, which has constitutive tyrosine kinase activity. The BCR-ABL1 fusion protein is produced from… read more here.

Keywords: cml; tki resistance; cobll1; resistance ... See more keywords