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Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.4177.4177
Abstract: Up- or down-regulation of many miRNAs plays an important role in chronic myeloid leukemia (CML), however underlying mechanisms remain to be elucidated. Here, we report miRNA-424 and miR-503 regulates Cobll1 expression during CML progression. In…
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Keywords:
mir 424;
mir 503;
mir;
cobll1 ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21705
Abstract: Chronic myeloid leukemia (CML) is a malignant cancer derived from hematopoietic stem cells. CML is induced by an oncogenic BCR-ABL1 fusion protein, which has constitutive tyrosine kinase activity. The BCR-ABL1 fusion protein is produced from…
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Keywords:
cml;
tki resistance;
cobll1;
resistance ... See more keywords