Glutamate receptor-interacting protein 1 in D1- and D2-dopamine receptor-expressing medium spiny neurons differentially regulates cocaine acquisition, reinstatement, and associated spine plasticity
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DOI: 10.3389/fncel.2022.979078
Abstract: Background The nucleus accumbens (NAc) is involved in the expression of cocaine addictive phenotypes, including acquisition, extinction, and reinstatement. In the NAc, D1-medium spiny neurons (MSNs) encode cocaine reward, whereas D2-MSNs encode aversive responses in… read more here.
Keywords: reinstatement; acquisition reinstatement; grip1; cocaine acquisition ... See more keywords