Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats
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DOI: 10.1016/j.brs.2021.11.003
Abstract: BACKGROUND Cocaine addiction is a major public health problem. Despite decades of intense research, no effective treatments are available. Both preclinical and clinical studies strongly suggest that deep brain stimulation of the nucleus accumbens (NAcc)… read more here.
Keywords: cocaine; cocaine dependent; shell; brain stimulation ... See more keywords
Unpacking common and distinct neuroanatomical alterations in cocaine dependent versus pathological gambling
Sign Up to like & getrecommendations! Published in 2020 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2020.01.019
Abstract: Pathological gambling and cocaine dependence are highly pervasive disorders. Functional neuroimaging evidence implicates aberrant activity of prefrontal striatal pathways in both disorders. It is unclear if the neuroanatomy of these areas is also affected. Participants… read more here.
Keywords: cocaine dependent; dependent versus; pathological gambling; alterations cocaine ... See more keywords