Dopamine D2 receptors mediate the increase in reinstatement of the conditioned rewarding effects of cocaine induced by acute social defeat
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.01.039
Abstract: Abstract Social stress modifies the activity of brain areas involved in the rewarding effects of psychostimulants, inducing neuroadaptations in the dopaminergic mesolimbic system and modifying the sensitivity of dopamine receptors. In the present study we… read more here.
Keywords: effects cocaine; cocaine induced; dopamine receptors; rewarding effects ... See more keywords
P.2.042 Cocaine-induced disruptions of information flow from the basolateral amygdala to the insula
Sign Up to like & getrecommendations! Published in 2018 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.12.081
Abstract: Understanding persistent dysregulations induced by chronic drug use on neuronal networks is crucial in order to develop appropriate therapeutic approach for addiction. The basolateral amygdala (BLA), involved in emotional processing, as well as the insular… read more here.
Keywords: information; bla; drug; basolateral amygdala ... See more keywords
Cocaine-induced multifocal leukoencephalopathy mimicking Balo's concentric sclerosis: A 2-year follow-up with serial imaging of a single patient.
Sign Up to like & getrecommendations! Published in 2018 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2017.11.011
Abstract: Cocaine abuse may cause stroke, metabolic or multifocal inflammatory leukoencephalopathy. We described a patient with cocaine abuse who presented with Balo's type acute multifocal leukoencephalopathy. Magnetic Resonance Imaging (MRI) of the brain showed onion like… read more here.
Keywords: sclerosis; concentric sclerosis; multifocal leukoencephalopathy; cocaine induced ... See more keywords
P53 knockout mice are protected from cocaine-induced kindling behaviors via inhibiting mitochondrial oxidative burdens, mitochondrial dysfunction, and proapoptotic changes
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2018.12.017
Abstract: ABSTRACT Previously we demonstrated that p53 mediates dopaminergic neurotoxicity via inducing mitochondrial burdens and proapoptotsis. However, little is known about the role of p53 in the excitotoxicity induced by psychostimulant, such as cocaine. Cocaine‐induced kindling… read more here.
Keywords: depletion p53; cocaine induced; oxidative burdens; cocaine ... See more keywords
Effects of ketosis on cocaine-induced reinstatement in male mice
Sign Up to like & getrecommendations! Published in 2022 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2022.136619
Abstract: In recent years, the benefits of the ketogenic diet (KD) on different psychiatric disorders have been gaining attention, but the substance abuse field is still unexplored. Some studies have reported that palatable food can modulate… read more here.
Keywords: effects cocaine; induced reinstatement; effects ketosis; ketosis cocaine ... See more keywords
The histone demethylase KDM6B in the medial prefrontal cortex epigenetically regulates cocaine reward memory
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.08.030
Abstract: ABSTRACT Epigenetic remodeling contributes to synaptic plasticity via modification of gene expression, which underlies cocaine‐induced long‐term memory. A prevailing hypothesis in drug addiction is that drugs of abuse rejuvenate developmental machinery to render reward circuitry… read more here.
Keywords: drug; cocaine induced; cocaine; memory ... See more keywords
Serotonin2B receptor blockade in the rat dorsal raphe nucleus suppresses cocaine-induced hyperlocomotion through an opposite control of mesocortical and mesoaccumbens dopamine pathways
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.108309
Abstract: Serotonin2B receptor (5-HT2BR) antagonists inhibit cocaine-induced hyperlocomotion independently of changes of accumbal dopamine (DA) release. Given the tight relationship between accumbal DA activity and locomotion, and the inhibitory role of medial prefrontal cortex (mPFC) DA… read more here.
Keywords: induced hyperlocomotion; cocaine induced; serotonin2b receptor; dorsal raphe ... See more keywords
Cocaine-induced increases in motivation require 2-arachidonoylglycerol mobilization and CB1 receptor activation in the ventral tegmental area
Sign Up to like & getrecommendations! Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108625
Abstract: A wide body of evidence supports an integral role for mesolimbic dopamine (DA) in motivated behavior. In brief, drugs that increase DA in mesolimbic terminal regions, like cocaine, enhance motivation, while drugs that decrease DA… read more here.
Keywords: cb1 receptor; cocaine induced; activation; cocaine ... See more keywords
Cannabidiol prevents several of the behavioral alterations related to cocaine addiction in mice
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2021.110390
Abstract: Cocaine dependence is a highly prevalent disease in modern society and lacks an effective treatment. Cannabidiol (CBD), a major non-psychoactive constituent of Cannabis sativa, has been shown to be a promising tool in the management… read more here.
Keywords: cocaine addiction; cocaine induced; cannabidiol; related cocaine ... See more keywords
When the front fails, the rear wins. Cerebellar correlates of prefrontal dysfunction in cocaine-induced memory in male rats
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2021.110429
Abstract: Reciprocal pathways connecting the cerebellum to the prefrontal cortex provide a biological and functional substrate to modulate cognitive functions. Dysfunction of both medial prefrontal cortex (mPFC) and cerebellum underlie the phenotypes of several neuropsychiatric disorders… read more here.
Keywords: male rats; cortex; drug; induced memory ... See more keywords
A case of cocaine-induced eosinophilic pneumonia: Case report and review of the literature
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2017.12.012
Abstract: Cocaine is a commonly abused recreational drug in the United States. An adult man developed non-specific pleuritic chest pain, pharyngitis and odynophagia after inhaling cocaine. Initial laboratory results revealed eosinophilia. Bronchoalveolar lavage also showed eosinophilia… read more here.
Keywords: eosinophilic pneumonia; cocaine induced; case cocaine; case ... See more keywords