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   Articles with "cocaine like" as a keyword



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Cocaine-like discriminative stimulus effects of “norepinephrine-preferring” monoamine releasers: time course and interaction studies in rhesus monkeys

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recommendations! Published in 2017 at "Psychopharmacology"

DOI: 10.1007/s00213-017-4731-5

Abstract: RationaleThe therapeutic potential of monoamine releasers with prominent dopaminergic effects is hindered by their high abuse liability.ObjectivesThe present study examined the effects of several novel “norepinephrine (NE)-preferring” monoamine releasers relative to non-selective monoamine releasers, d-amphetamine… read more here.

Keywords: preferring monoamine; cocaine like; cocaine; like discriminative ... See more keywords
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Role of d-amphetamine and d-methamphetamine as active metabolites of benzphetamine: Evidence from drug discrimination and pharmacokinetic studies in male rhesus monkeys

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recommendations! Published in 2017 at "Pharmacology Biochemistry and Behavior"

DOI: 10.1016/j.pbb.2017.03.008

Abstract: ABSTRACT Benzphetamine is a Schedule III anorectic agent that is a prodrug for d‐amphetamine and d‐methamphetamine and may have utility as an “agonist” medication for cocaine use disorder treatment. This study evaluated the pharmacokinetic‐pharmacodynamic profile… read more here.

Keywords: amphetamine; behavioral effects; rhesus monkeys; cocaine like ... See more keywords
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Cocaine‐like discriminative stimulus effects of alpha‐pyrrolidinovalerophenone, methcathinone and their 3,4‐methylenedioxy or 4‐methyl analogs in rhesus monkeys

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recommendations! Published in 2017 at "Addiction Biology"

DOI: 10.1111/adb.12399

Abstract: Synthetic cathinones are beta‐ketone amphetamine analogs that have emerged as a heterogeneous class of abused compounds that function as either monoamine transporter substrates or inhibitors. Pre‐clinical drug discrimination procedures are useful for interrogating structure–activity relationships… read more here.

Keywords: stimulus effects; discriminative stimulus; cocaine like; cocaine ... See more keywords