Recent insights into gap junction biogenesis in the cochlea
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.538
Abstract: In the cochlea, connexin 26 (Cx26) and connexin 30 (Cx30) co‐assemble into two types of homomeric and heteromeric gap junctions between adjacent non‐sensory epithelial cells. These channels provide a mechanical coupling between connected cells, and… read more here.
Keywords: recent insights; cx30; cochlea; biogenesis ... See more keywords
Cochlear Capillary Pericytes.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-11093-2_7
Abstract: Capillary pericytes in the cochlea of mammals are-compared to pericytes in other tissues, like the CNS-relatively poorly researched. To begin with, there is still a considerable debate as to whether the very last precapillary arterioles… read more here.
Keywords: cochlea; physiology; cochlear capillary; blood ... See more keywords
[Intracochlear schwannoma : Tumor removal via subtotal cochleoectomy and partial cochlear reconstruction with preservation of semicircular canal function. German version].
Sign Up to like & getrecommendations! Published in 2017 at "HNO"
DOI: 10.1007/s00106-017-0347-7
Abstract: We report about a patient who in 2005, aged 37 years, experienced sudden mild to moderate, mid-frequency sensorineural hearing loss in the right ear along with tinnitus and mild dizziness. MRI of the temporal bone revealed… read more here.
Keywords: cochleoectomy; removal; subtotal cochleoectomy; cochlea ... See more keywords
Intracochlear schwannoma
Sign Up to like & getrecommendations! Published in 2017 at "HNO"
DOI: 10.1007/s00106-017-0348-6
Abstract: We report about a patient, who in 2005, as a 37-year-old, experienced a sudden, mild to moderate, mid-frequency sensorineural hearing loss in the right ear, along with tinnitus and mild dizziness. MRI of the temporal bone revealed a very… read more here.
Keywords: cochlea; hearing loss; intracochlear schwannoma;
T2 relaxation time shortening in the cochlea of patients with sudden sensory neuronal hearing loss: a retrospective study using quantitative synthetic magnetic resonance imaging
Sign Up to like & getrecommendations! Published in 2021 at "European Radiology"
DOI: 10.1007/s00330-021-07749-5
Abstract: High cochlear signal intensity on three-dimensional (3D) T2 fluid-attenuated inversion recovery (FLAIR) sequences in patients with sudden sensorineural hearing loss (SSNHL) has been reported. Here, we evaluated the cochlear T2 relaxation time differences in patients… read more here.
Keywords: cochlea; relaxation time; signal intensity; relaxation ... See more keywords
Evaluation of endolymphatic hydrops using 3-T MRI after intravenous gadolinium injection
Sign Up to like & getrecommendations! Published in 2017 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-017-4739-9
Abstract: AbstractAim of this work is to establish evaluation criteria for identifying endolymphatic hydrops in the vestibule and cochlea using a magnetic resonance imaging (MRI) scanner. This is a retrospective diagnostic study. We evaluated 70 ears… read more here.
Keywords: endolymphatic hydrops; cochlea; endolymphatic space; vestibule cochlea ... See more keywords
Upregulation of HSP60 expression in the postnatal rat cochlea and rats with drug-induced hearing loss
Sign Up to like & getrecommendations! Published in 2018 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-018-0938-6
Abstract: Heat shock protein 60 (HSP60) is a highly conserved chaperone molecule that plays important roles in mediating some physiological and pathological functions. However, researchers have not yet determined whether HSP60 is expressed in the mammalian… read more here.
Keywords: drug; cochlea; expression; rat cochlea ... See more keywords
Differential Phase Arrangement of Cellular Clocks along the Tonotopic Axis of the Mouse Cochlea Ex Vivo
Sign Up to like & getrecommendations! Published in 2017 at "Current Biology"
DOI: 10.1016/j.cub.2017.07.019
Abstract: Topological distributions of individual cellular clocks have not been demonstrated in peripheral organs. The cochlea displays circadian patterns of core clock gene expression [1, 2]. PER2 protein is expressed in the hair cells and spiral… read more here.
Keywords: tonotopic axis; along tonotopic; cellular clocks; cochlea ... See more keywords
Reduced mitophagy in the cochlea of aged C57BL/6J mice
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2020.110946
Abstract: An increase in mitochondrial damage has been associated with a decline in the ability to mitigate damage through mitophagy in age-related pathologies. The present study aimed to investigate the changes of mitophagy in a mouse… read more here.
Keywords: cochlea mice; mice aged; cochlea; mice ... See more keywords
No effect of prolonged pulsed high frequency ultrasound imaging of the basilar membrane on cochlear function or hair cell survival found in an initial study
Sign Up to like & getrecommendations! Published in 2018 at "Hearing Research"
DOI: 10.1016/j.heares.2017.12.006
Abstract: &NA; Miniature high frequency ultrasound devices show promise as tools for clinical middle ear and basal cochlea imaging and vibrometry. However, before clinical use it is important to verify that the ultrasound exposure does not… read more here.
Keywords: initial study; high frequency; frequency; hair ... See more keywords
Unusual mechanical processing of sounds at the apex of the Guinea pig cochlea
Sign Up to like & getrecommendations! Published in 2018 at "Hearing Research"
DOI: 10.1016/j.heares.2018.09.009
Abstract: ABSTRACT One of the tenets of mammalian auditory physiology is that the frequency selectivity at the cochlear base decreases as a function of stimulus level. Changes in frequency selectivity have been shown to be accompanied… read more here.
Keywords: guinea pig; frequency selectivity; cochlea; pig cochlea ... See more keywords