Cochlear amplification and tuning depend on the cellular arrangement within the organ of Corti
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1720979115
Abstract: Significance While the near-crystalline structure of the organ-of-Corti cytoarchitecture in the mammalian cochlea has been known for some time, its functional consequences on hearing remain to be established. The present computational-modeling studies show that individual… read more here.
Keywords: tuning depend; organ corti; cochlear amplification; geometry ... See more keywords
Prestin's fast motor kinetics is essential for mammalian cochlear amplification.
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DOI: 10.1073/pnas.2217891120
Abstract: Prestin (SLC26A5)-mediated voltage-driven elongations and contractions of sensory outer hair cells within the organ of Corti are essential for mammalian cochlear amplification. However, whether this electromotile activity directly contributes on a cycle-by-cycle basis is currently… read more here.
Keywords: motor kinetics; cochlear amplification; essential mammalian; mammalian cochlear ... See more keywords
The impact of targeted ablation of one row of outer hair cells and Deiters' cells on cochlear amplification.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurophysiology"
DOI: 10.1152/jn.00501.2021
Abstract: The mammalian cochlea contains three rows of outer hair cells (OHCs) that amplify the basilar membrane traveling wave with high gain and exquisite tuning. The pattern of OHC loss caused by typical methods of producing… read more here.
Keywords: deiters cells; hair cells; amplification; row ... See more keywords