Verapamil and riluzole cocktail liposomes overcome pharmacoresistance by inhibiting P‐glycoprotein in brain endothelial and astrocyte cells: A potent approach to treat amyotrophic lateral sclerosis
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DOI: 10.1016/j.ejps.2018.04.026
Abstract: &NA; Riluzole is currently one of two approved medications for the treatment of amyotrophic lateral sclerosis (ALS). However, brain disposition of riluzole, as a substrate of P‐glycoprotein (P‐gp), is limited by the efflux transporters at… read more here.
Keywords: cocktail liposomes; amyotrophic lateral; cocktail; verapamil riluzole ... See more keywords