Hypoxia‐induced SPOP attenuates the mobility of trophoblast cells through inhibition of the PI3K/AKT/GSK3β pathway
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biology International"
DOI: 10.1002/cbin.11501
Abstract: Placental hypoxia has been implicated in pregnancy pathologies such as pre‐eclampsia and intrauterine growth restriction. However, the underlying mechanism by which the trophoblasts respond to hypoxia remains unclear. Speckle‑type POZ protein (SPOP), an E3 ubiquitin… read more here.
Keywords: pi3k akt; hypoxia; gsk3 pathway; cocl2 ... See more keywords
The paracrine effect of cobalt chloride on BMSCs during cognitive function rescue in the HIBD rat
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.05.055
Abstract: &NA; Hypoxia–ischemia (HI)‐induced perinatal encephalopathy frequently causes chronic neurological morbidities and acute mortality. Bone mesenchymal stem cell (BMSC) transplantation could potentially promote functional and anatomical recovery of ischemic tissue. In vitro hypoxic preconditioning is an… read more here.
Keywords: cocl2 preconditioned; medium; preconditioned bmsc; cobalt chloride ... See more keywords
Discordant mRNA and protein expression of CXCR4 under in vitro CoCl2-induced hypoxic conditions.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.102
Abstract: Cobalt chloride (CoCl2) has long been accepted as a suitable in vitro hypoxia-mimetic agent. The gene CXCR4, which encodes a chemokine receptor, plays a key role in hypoxic retinal disease. Here, we investigated the mRNA and… read more here.
Keywords: mrna protein; hypoxic conditions; cocl2 induced; cocl2 ... See more keywords
Moringa oleifera leaves ethanolic extract influences DNA damage signaling pathways to protect liver tissue from cobalt -triggered apoptosis in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.110716
Abstract: This study assessed the potential of Moringa oleifera leaves ethanol extract (MLEE) in attenuating the detrimental effects of cobalt dichloride (CoCl2) on rat liver. Forty rats were assigned to five equal groups: control group, MLEE-treated… read more here.
Keywords: dna damage; moringa oleifera; group; oleifera leaves ... See more keywords
Protective roles of NRF2 signaling pathway in cobalt chloride‐induced hypoxic cytotoxicity in human HaCaT keratinocytes
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.06.030
Abstract: ABSTRACT Hypoxia is a key pathological process involved in many cutaneous diseases. Nuclear factor E2‐related factor 2 (NRF2) is a central regulator of antioxidant response element (ARE)‐dependent transcription and plays a pivotal role in the… read more here.
Keywords: nrf2 signaling; signaling pathway; hacat cells; hacat ... See more keywords
Metal-Decorated Phthalocyanine Monolayer as a Potential Gas Sensing Material for Phosgene: A First-Principles Study
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c02548
Abstract: Research into a gas sensing material with excellent performance to detect or remove toxic phosgene (COCl2) is of great significance to environmental and biological protection. In the present work, the adsorption performance of COCl2 on… read more here.
Keywords: gas sensing; adsorption; phosgene; cocl2 ... See more keywords
Enhancement of the antiproliferative activity of [RuCp(PPh3)2(dmoPTA-1κP)]+via its coordination to one {CoCl2} unit: synthesis, crystal structure and properties of [RuCp(PPh3)2-μ-dmoPTA-1κP:2κ2N,N'-CoCl2](OTf)·0.25H2O.
Sign Up to like & getrecommendations! Published in 2017 at "Dalton transactions"
DOI: 10.1039/c7dt01741c
Abstract: Synthesis, characterization and the antiproliferative activity of a new bimetallic complex [RuCp(PPh3)2-μ-dmoPTA-1κP:2k2N,N'-CoCl2]OTf·0.25H2O are described. The stability of the complex was studied under air and N2 atmospheres and in CDCl3, DMSO, water and the cell culture… read more here.
Keywords: pph3 dmopta; rucp pph3; antiproliferative activity; cocl2 ... See more keywords
Adsorption sensitivity of pristine and Al- or Si-doped boron nitride nanoflake to COCl2: a DFT study
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Physics"
DOI: 10.1080/00268976.2018.1532538
Abstract: ABSTRACT The adsorption of phosgene (COCl2) on pristine, Al- and Si-doped boron nitride nanoflakes (BNNFs) is studied using density functional theory calculations. The adsorption energies of the most stable complexes, formed from interaction between COCl2… read more here.
Keywords: adsorption; pristine doped; boron nitride; doped boron ... See more keywords
Ameliorative Effects of Extracellular Vesicles Derived from Mesenchymal Stem Cells on Apoptosis and Differentiation of Osteoblasts Treated with CoCl2.
Sign Up to like & getrecommendations! Published in 2023 at "Cellular reprogramming"
DOI: 10.1089/cell.2023.0001
Abstract: Severe osteoporotic fracture occurring in sites with inadequate blood supply can cause irreversible damage to cells, particularly osteoblasts, with current drug and surgical interventions exhibiting limitations for elderly individuals. As participants mediating intercellular communication, extracellular… read more here.
Keywords: extracellular vesicles; mesenchymal stem; cocl2; differentiation ... See more keywords
T32. NEONATAL CHEMICAL HYPOXIA EXPOSURE CAUSES NEURONAL AND BEHAVIORAL ALTERATIONS RELATED TO SCHIZOPHRENIA IN WISTAR RATS
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbaa029.592
Abstract: Abstract Background Schizophrenia (SZ) is a complex and debilitating mental disorder that affects approximately 1% of the world population and, according to the World Health Organization, it is one of the top ten causes of… read more here.
Keywords: neuronal behavioral; chemical hypoxia; hypoxia; wistar rats ... See more keywords
PGC‐1 alpha regulates mitochondrial biogenesis to ameliorate hypoxia‐inhibited cementoblast mineralization
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14872
Abstract: Hypoxia often occurs in inflammatory tissues, such as tissues affected by periodontitis and apical periodontitis lesions. Mitochondrial biogenesis can be disrupted in hypoxia. Peroxisome proliferator‐activated receptor gamma coactivator‐1 alpha (PGC‐1α) is a core factor required… read more here.
Keywords: mitochondrial biogenesis; biogenesis; hypoxia; cocl2 ... See more keywords