Discordant mRNA and protein expression of CXCR4 under in vitro CoCl2-induced hypoxic conditions.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.102
Abstract: Cobalt chloride (CoCl2) has long been accepted as a suitable in vitro hypoxia-mimetic agent. The gene CXCR4, which encodes a chemokine receptor, plays a key role in hypoxic retinal disease. Here, we investigated the mRNA and… read more here.
Keywords: mrna protein; hypoxic conditions; cocl2 induced; cocl2 ... See more keywords
Propofol protects PC12 cells from cobalt chloride -induced injury by mediating miR-134.
Sign Up to like & getrecommendations! Published in 2021 at "Histology and histopathology"
DOI: 10.14670/hh-18-298
Abstract: OBJECTIVE Propofol (PRO) was reported to exert a neuroprotective effect by decreasing microRNA-134 (miR-134), a brain-specific miRNA, thus, the role of PRO against cobalt chloride (CoCl2)-induced injury in rat pheochromocytoma cells (PC12) via mediating miR-134… read more here.
Keywords: mir 134; cocl2 induced; pc12 cells; cobalt chloride ... See more keywords
Assessing the protective effects of cryptotanshinone on CoCl2-induced hypoxia in RPE cells
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2021.12379
Abstract: The development of several retinal diseases is closely related to hypoxia. As a component of the Traditional Chinese medicine Salvia miltiorrhiza, the effects of cryptotanshinone (CT) on retinal cells under hypoxic conditions are not well… read more here.
Keywords: medicine; effects cryptotanshinone; rpe cells; cocl2 induced ... See more keywords