Articles with "cocl2 induced" as a keyword



Discordant mRNA and protein expression of CXCR4 under in vitro CoCl2-induced hypoxic conditions.

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Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.01.102

Abstract: Cobalt chloride (CoCl2) has long been accepted as a suitable in vitro hypoxia-mimetic agent. The gene CXCR4, which encodes a chemokine receptor, plays a key role in hypoxic retinal disease. Here, we investigated the mRNA and… read more here.

Keywords: mrna protein; hypoxic conditions; cocl2 induced; cocl2 ... See more keywords

Resveratrol attenuates the CoCl2-induced hypoxia damage by regulation of lysine β-hydroxybutyrylation in PC12 cells

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Published in 2025 at "BMC Neurology"

DOI: 10.1186/s12883-025-04171-y

Abstract: Stroke is a cerebrovascular disease that is the main cause of death and disability worldwide. Hypoxia is a major factor that causes neuronal damage and even cellular death. However, the mechanism and therapeutic drugs for… read more here.

Keywords: cocl2 induced; pc12 cells; pc12; hypoxia damage ... See more keywords

Propofol protects PC12 cells from cobalt chloride -induced injury by mediating miR-134.

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Published in 2021 at "Histology and histopathology"

DOI: 10.14670/hh-18-298

Abstract: OBJECTIVE Propofol (PRO) was reported to exert a neuroprotective effect by decreasing microRNA-134 (miR-134), a brain-specific miRNA, thus, the role of PRO against cobalt chloride (CoCl2)-induced injury in rat pheochromocytoma cells (PC12) via mediating miR-134… read more here.

Keywords: mir 134; cocl2 induced; pc12 cells; cobalt chloride ... See more keywords

Assessing the protective effects of cryptotanshinone on CoCl2-induced hypoxia in RPE cells

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Published in 2021 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2021.12379

Abstract: The development of several retinal diseases is closely related to hypoxia. As a component of the Traditional Chinese medicine Salvia miltiorrhiza, the effects of cryptotanshinone (CT) on retinal cells under hypoxic conditions are not well… read more here.

Keywords: medicine; effects cryptotanshinone; rpe cells; cocl2 induced ... See more keywords