Novel cocrystals of the potent 1,2,4-thiadiazole-based neuroprotector with carboxylic acids: virtual screening, crystal structures and solubility performance
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DOI: 10.1039/d0nj05644h
Abstract: Five new multicomponent solid forms of the biologically active 1,2,4-thiadiazole derivative (TDZH) with dicarboxylic and hydroxybenzoic acids have been discovered by combined virtual/experimental cocrystal screening. The interplay between the intrinsic hierarchy of the donor/acceptor groups… read more here.
Keywords: neuroprotector carboxylic; thiadiazole based; cocrystals potent; based neuroprotector ... See more keywords