CNEFinder: finding conserved non-coding elements in genomes
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/bty601
Abstract: Motivation Conserved non‐coding elements (CNEs) represent an enigmatic class of genomic elements which, despite being extremely conserved across evolution, do not encode for proteins. Their functions are still largely unknown. Thus, there exists a need… read more here.
Keywords: conserved non; finding conserved; cnefinder finding; non coding ... See more keywords
Conserved non-coding elements: developmental gene regulation meets genome organization
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1074
Abstract: Abstract Comparative genomics has revealed a class of non-protein-coding genomic sequences that display an extraordinary degree of conservation between two or more organisms, regularly exceeding that found within protein-coding exons. These elements, collectively referred to… read more here.
Keywords: conserved non; gene regulation; developmental gene; elements developmental ... See more keywords
Long-Read Sequencing Improves the Detection of Structural Variations Impacting Complex Non-Coding Elements of the Genome
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22042060
Abstract: The advent of long-read sequencing offers a new assessment method of detecting genomic structural variation (SV) in numerous rare genetic diseases. For autism spectrum disorders (ASD) cases where pathogenic variants fail to be found in… read more here.
Keywords: long read; read sequencing; elements genome; impacting complex ... See more keywords