Loss of the IR region in conifer plastomes: Changes in the selection pressure and substitution rate of protein‐coding genes
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.8499
Abstract: Abstract Plastid genomes (plastomes) have a quadripartite structure, but some species have drastically reduced or lost inverted repeat (IR) regions. IR regions are important for genome stability and the evolution rate. In the evolutionary process… read more here.
Keywords: rate; coding genes; selection pressure; selection ... See more keywords
The development and controversy of competitive endogenous RNA hypothesis in non-coding genes
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-020-03889-2
Abstract: As a momentous post-transcriptional regulator, microRNAs (miRNAs) are attracting more and more attention. The classical miRNAs regulated mechanism shows it binds to the targets’ 3′UTR thus play the role in post-transcription. Meanwhile, single miRNA can… read more here.
Keywords: controversy; competitive endogenous; non coding; hypothesis ... See more keywords
Genes dysregulated in the blood of people with Williams syndrome are enriched in protein-coding genes positively selected in humans.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medical genetics"
DOI: 10.1016/j.ejmg.2019.103828
Abstract: Williams syndrome is a complex condition resulting from the heterozygous deletion of nearly 30 genes in chromosome 7. However, precise genotype-to-phenotype mappings are not available for most of its distinctive features. Because WS entails changes… read more here.
Keywords: enriched protein; protein coding; williams syndrome; dysregulated blood ... See more keywords
Long-term evolutionary DNA methylation dynamic of protein-coding genes and its underlying mechanism.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.07.051
Abstract: DNA methylation is an important type of epigenetic modifications for the maintenance of genome functionality and stability. Although there are many studies on DNA methylation patterns, mechanisms, and functions, no study has focused on the… read more here.
Keywords: protein coding; methylation; dna methylation; coding genes ... See more keywords
Five new mitogenomes of Phylloscopus (Passeriformes, Phylloscopidae): Sequence, structure, and phylogenetic analyses.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.12.253
Abstract: The genus Phylloscopus belongs to the order Passeriformes and subfamily Phylloscopinae within the family Sylviidae. Phylloscopus, a small insectivore widely distributed in the old world, includes 66 species and 112 subspecies. We identified five new… read more here.
Keywords: new mitogenomes; five new; phylloscopus; protein coding ... See more keywords
Translocation breakpoint disrupting the host SNHG14 gene but not coding genes or snoRNAs in typical Prader-Willi syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Human Genetics"
DOI: 10.1038/s10038-019-0596-2
Abstract: Prader–Willi syndrome (PWS) is a well-known imprinting disorder arising from a loss of paternally imprinted gene(s) at 15q11.2–q13. We report a typical PWS patient with a balanced reciprocal translocation, 46, XY, t(15;19)(q11.2;q13.3). After Illumina whole-genome… read more here.
Keywords: breakpoint; willi syndrome; prader willi; gene ... See more keywords
Analysis of diet-induced differential methylation, expression, and interactions of lncRNA and protein-coding genes in mouse liver
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29993-4
Abstract: Long non-coding RNAs (lncRNAs) regulate expression of protein-coding genes in cis through chromatin modifications including DNA methylation. Here we interrogated whether lncRNA genes may regulate transcription and methylation of their flanking or overlapping protein-coding genes… read more here.
Keywords: methylation; expression; lncrna protein; protein coding ... See more keywords
Top-ranked expressed gene transcripts of human protein-coding genes investigated with GTEx dataset
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73081-5
Abstract: With considerable accumulation of RNA-Seq transcriptome data, we have extended our understanding about protein-coding gene transcript compositions. However, alternatively compounded patterns of human protein-coding gene transcripts would complicate gene expression data processing and interpretation. It… read more here.
Keywords: human protein; protein coding; top ranked; coding genes ... See more keywords
MicroRNAs in neural crest development and neurocristopathies
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society Transactions"
DOI: 10.1042/bst20210828
Abstract: The neural crest (NC) is a vertebrate-specific migratory population of multipotent stem cells that originate during late gastrulation in the region between the neural and non-neural ectoderm. This population of cells give rise to a… read more here.
Keywords: development neurocristopathies; neural crest; development; micrornas neural ... See more keywords
LncRNAs in molluscan and mammalian stages of parasitic schistosomes are developmentally-regulated and coordinately expressed with protein-coding genes
Sign Up to like & getrecommendations! Published in 2020 at "RNA Biology"
DOI: 10.1080/15476286.2020.1729594
Abstract: ABSTRACT Despite the low level expression of some long noncoding RNAs (lncRNAs), the differential expression of specific lncRNAs plays important roles during the development of many organisms. Schistosomes, parasitic flatworms that are responsible for schistosomiasis,… read more here.
Keywords: molluscan mammalian; lncrnas molluscan; expression; protein coding ... See more keywords
From De Novo to “De Nono”: The Majority of Novel Protein-Coding Genes Identified with Phylostratigraphy Are Old Genes or Recent Duplicates
Sign Up to like & getrecommendations! Published in 2018 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evy231
Abstract: Abstract The evolution of novel protein-coding genes from noncoding regions of the genome is one of the most compelling pieces of evidence for genetic innovations in nature. One popular approach to identify de novo genes… read more here.
Keywords: novel protein; novo genes; phylostratigraphy; protein coding ... See more keywords