Codon adaptation by synonymous mutations impacts the functional properties of the estrogen receptor-alpha protein in breast cancer cells.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13399
Abstract: Estrogen receptor-alpha (ERĪ±) positivity is intimately associated with the development of hormone-dependent breast cancers. A major challenge in the treatment of these cancers is to understand and overcome the mechanisms of endocrine resistance. Recently, two… read more here.
Keywords: estrogen receptor; codon adaptation; receptor alpha; functional properties ... See more keywords
Codon adaptation biases among sylvatic and urban genotypes of Dengue virus type 2
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DOI: 10.1016/j.meegid.2018.05.017
Abstract: Abstract Dengue virus (DENV) emerged from the sylvatic environment and colonized urban settings, being sustained in a human-Aedes-human transmission chain, mainly by the bites of females of the anthropophilic species Aedes aegypti. Herein, we sought… read more here.
Keywords: sylvatic urban; dengue virus; urban genotypes; codon adaptation ... See more keywords
Utilizing the codon adaptation index to evaluate the susceptibility to HIV-1 and SARS-CoV-2 related coronaviruses in possible target cells in humans
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1085397
Abstract: Comprehensive identification of possible target cells for viruses is crucial for understanding the pathological mechanism of virosis. The susceptibility of cells to viruses depends on many factors. Besides the existence of receptors at the cell… read more here.
Keywords: hiv sars; susceptibility; codon adaptation; target cells ... See more keywords