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   Articles with "codon mutations" as a keyword



Association of various RAS codon mutations and prognostic outcomes of patients with colorectal liver metastases after hepatectomy

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recommendations! Published in 2024 at "Cancer Medicine"

DOI: 10.1002/cam4.70168

Abstract: The prognostic and predictive value of RAS mutations in patients with colorectal liver metastases (CRLM) who have undergone hepatectomy holds substantial importance. The present study aimed to investigate the impact of different RAS codon mutations… read more here.

Keywords: patients colorectal; liver metastases; codon mutations; colorectal liver ... See more keywords

Clinical Predictors for KRAS Codon 13 Mutations in Patients With Colorectal Cancer

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recommendations! Published in 2018 at "Journal of Clinical Gastroenterology"

DOI: 10.1097/mcg.0000000000000809

Abstract: Goals: This study sought to clarify sex differences in KRAS mutations and clinical predictors of KRAS 13 codon mutations. Background: Sex differences in KRAS mutations and predictors for KRAS codon 13 mutations in colorectal cancer… read more here.

Keywords: sex differences; predictors kras; codon mutations; kras codon ... See more keywords

RAS G12 and Q61 codon mutations confer distinct disease characteristics in Acute Myeloid Leukemia and exhibit differential response to RAS(ON) inhibitor RMC-7977.

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recommendations! Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-3229

Abstract: RAS pathway mutations are present in 10-20% of acute myeloid leukemia (AML) cases at diagnosis, and frequently occur as late, subclonal events in leukemogenesis. Bulk sequencing studies have demonstrated that NRAS mutations are most frequent,… read more here.

Keywords: disease; response; codon mutations; rmc ... See more keywords

KRAS exon 2 codon 13 mutation is associated with a better prognosis than codon 12 mutation following lung metastasectomy in colorectal cancer

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.13697

Abstract: Introduction The utilization of molecular markers as routinely used biomarkers is steadily increasing. We aimed to evaluate the potential different prognostic values of KRAS exon 2 codons 12 and 13 after lung metastasectomy in colorectal… read more here.

Keywords: associated better; kras exon; codon mutation; lung metastasectomy ... See more keywords