Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2.
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DOI: 10.1016/j.virol.2019.09.003
Abstract: The four serotypes of dengue virus (DENV) are the leading etiologic agent of disease caused by arthropod-borne viruses (arboviruses) in the world, with billions at risk of DENV infection spread by infected mosquitoes. DENV causes… read more here.
Keywords: codon; codon pair; dengue virus; vaccine candidates ... See more keywords