Coexpression network analysis identified Krüppel‐like factor 6 (KLF6) association with chemosensitivity in ovarian cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27567
Abstract: Although most patients with ovarian cancer (OC) are initially sensitive to paclitaxel/carboplatin combination chemotherapy, eventually they develop resistance to chemotherapy drugs and experience disease relapse. OC is the most lethal gynecological malignancy, and the five‐year… read more here.
Keywords: network; analysis; ppel like; ovarian cancer ... See more keywords
Comparative Analysis of Core and Accessory Genes in Coexpression Network.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1099-2_3
Abstract: Prokaryotes harbor a various proportion of accessory genes in their genomes. The integration of accessory functions with the core regulation network is critical for environmental adaptation, particularly considering a theoretically unlimited number of niches on… read more here.
Keywords: comparative analysis; network; core accessory; accessory genes ... See more keywords
Immune response gene coexpression network analysis of Arachis hypogaea infected with Aspergillus flavus.
Sign Up to like & getrecommendations! Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.06.027
Abstract: Aspergillus flavus (A. flavus) infection and aflatoxin contamination is a major bottleneck for peanut cultivation and value chain industry. In this study, a transcriptomic network study was conducted by retrieving publically available RNA-seq datasets of… read more here.
Keywords: network; response; analysis; immune response ... See more keywords
Coexpression network analysis reveals an MYB transcriptional activator involved in capsaicinoid biosynthesis in hot peppers.
Sign Up to like & getrecommendations! Published in 2020 at "Horticulture research"
DOI: 10.1038/s41438-020-00381-2
Abstract: Plant biosynthesis involves numerous specialized metabolites with diverse chemical natures and biological activities. The biosynthesis of metabolites often exclusively occurs in response to tissue-specific combinatorial developmental cues that are controlled at the transcriptional level. Capsaicinoids… read more here.
Keywords: biosynthesis; capsaicinoid biosynthesis; coexpression network; transcriptional activator ... See more keywords
Gene coexpression network analysis identifies hubs in hepatitis B virus–associated hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000772
Abstract: Background: Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related death worldwide. The molecular pathogenesis of HCC involves multiple signaling pathways. This study utilizes systems and bioinformatic approaches to investigate the pathogenesis of HCC.… read more here.
Keywords: network; gene coexpression; coexpression network; analysis ... See more keywords
A Global Coexpression Network Approach for Connecting Genes to Specialized Metabolic Pathways in Plants
Sign Up to like & getrecommendations! Published in 2017 at "Plant Cell"
DOI: 10.1105/tpc.17.00009
Abstract: Global gene coexpression network analysis is a powerful approach for identifying known and novel plant-specialized metabolic pathways, irrespective of the genomic location of the constitutive genes. Plants produce diverse specialized metabolites (SMs), but the genes… read more here.
Keywords: coexpression; plant; metabolic pathways; specialized metabolic ... See more keywords
Weighted gene coexpression network analysis reveals hub genes involved in cholangiocarcinoma progression and prognosis
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology Research"
DOI: 10.1111/hepr.13386
Abstract: Cholangiocarcinoma (CCA) is a highly malignant tumor found in the bile duct epithelial cells, and the second most common primary tumor of the liver. However, the pivotal roles of molecular biomarkers in oncogenesis of CCA… read more here.
Keywords: analysis reveals; weighted gene; gene coexpression; progression ... See more keywords
Identification of Key Genes in Severe Burns by Using Weighted Gene Coexpression Network Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/5220403
Abstract: The aims of this work were to explore the use of weighted gene coexpression network analysis (WGCNA) for identifying the key genes in severe burns and to provide a reference for finding therapeutic targets for… read more here.
Keywords: network; weighted gene; gene coexpression; coexpression network ... See more keywords
Weighted Gene Coexpression Network Analysis Identifies Specific Modules and Hub Genes Related to Major Depression
Sign Up to like & getrecommendations! Published in 2020 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s244452
Abstract: Purpose Despite advances in characterizing the neurobiology of emotional disorders, there is still a significant lack of scientific understanding of the pathophysiological mechanisms governing major depressive disorder (MDD). This study attempted to elucidate the molecular… read more here.
Keywords: weighted gene; gene coexpression; analysis; gene ... See more keywords
Construction and Analysis of Coexpression Network to Understand Biological Responses in Chickens Infected by Eimeria tenella
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.688684
Abstract: Coccidiosis, caused by various Eimeria species, is a major parasitic disease in chickens. Our understanding of how chickens respond to coccidian infections is highly limited at both the molecular and cellular levels. In this study,… read more here.
Keywords: chickens infected; analysis; tenella; biological responses ... See more keywords
Identification of key gene modules and hub genes of human mantle cell lymphoma by coexpression network analysis
Sign Up to like & getrecommendations! Published in 2020 at "PeerJ"
DOI: 10.7717/peerj.8843
Abstract: Purpose Mantle cell lymphoma (MCL) is a rare and aggressive subtype of non-Hodgkin lymphoma that is incurable with standard therapies. The use of gene expression analysis has been of interest, recently, to detect biomarkers for… read more here.
Keywords: analysis; hub genes; gene; coexpression network ... See more keywords