Robust normalization and transformation techniques for constructing gene coexpression networks from RNA-seq data
Sign Up to like & getrecommendations! Published in 2022 at "Genome Biology"
DOI: 10.1186/s13059-021-02568-9
Abstract: Background Constructing gene coexpression networks is a powerful approach for analyzing high-throughput gene expression data towards module identification, gene function prediction, and disease-gene prioritization. While optimal workflows for constructing coexpression networks, including good choices for… read more here.
Keywords: coexpression networks; rna seq; coexpression; transformation ... See more keywords
Estimating Linear and Nonlinear Gene Coexpression Networks by Semiparametric Neighborhood Selection
Sign Up to like & getrecommendations! Published in 2020 at "Genetics"
DOI: 10.1534/genetics.120.303186
Abstract: Whereas nonlinear relationships between genes are acknowledged, there exist only a few methods for estimating nonlinear gene coexpression networks or gene regulatory networks (GCNs/GRNs) with common deficiencies. These methods often consider only pairwise associations between… read more here.
Keywords: linear nonlinear; gene coexpression; semiparametric neighborhood; nonlinear gene ... See more keywords