Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.
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DOI: 10.1016/j.cmet.2018.04.009
Abstract: Kidney cancer, one of the ten most prevalent malignancies in the world, has exhibited increased incidence over the last decade. The most common subtype is "clear cell" renal cell carcinoma (ccRCC), which features consistent metabolic… read more here.
Keywords: carcinoma; arginase; biosynthetic cofactor; pyridoxal phosphate ... See more keywords