Electrospray technology as a probe for cocrystal synthesis: Influence of solvent and coformer structure
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2017.04.001
Abstract: Abstract In the present work electrospray technology has been used for cocrystal synthesis of structurally diverse drug molecules. Additionally, influence of solvent and coformer structure on generation of pharmaceutical cocrystals was also investigated. Carbamazepine (CBZ)… read more here.
Keywords: electrospray technology; influence solvent; coformer; cocrystal synthesis ... See more keywords
Coupling complementary strategy to flexible graph neural network for quick discovery of coformer in diverse co-crystal materials.
Sign Up to like & getrecommendations! Published in 2021 at "Nature communications"
DOI: 10.1038/s41467-021-26226-7
Abstract: Cocrystal engineering have been widely applied in pharmaceutical, chemistry and material fields. However, how to effectively choose coformer has been a challenging task on experiments. Here we develop a graph neural network (GNN) based deep… read more here.
Keywords: neural network; coupling complementary; graph neural; coformer ... See more keywords
A new polymorph of the common coformer isonicotinamide
Sign Up to like & getrecommendations! Published in 2019 at "CrystEngComm"
DOI: 10.1039/c8ce01588k
Abstract: A polymorph of the widely employed coformer isonicotinamide crystallizing in the space group Pca21 is described for the first time. read more here.
Keywords: common coformer; coformer; new polymorph; coformer isonicotinamide ... See more keywords