In-depth study of DNA binding of Cys2His2 finger domains in testis zinc-finger protein
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DOI: 10.1371/journal.pone.0175051
Abstract: Previously, we identified that both fingers 1 and 2 in the three Cys2His2 zinc-finger domains (TZD) of testis zinc-finger protein specifically bind to its cognate DNA; however, finger 3 is non-sequence–specific. To gain insights into… read more here.
Keywords: dna; zinc finger; dna binding; finger ... See more keywords
Cognate DNA Recognition by Engrailed Homeodomain Involves A Conformational Change Controlled via An Electrostatic-Spring-Loaded Latch
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DOI: 10.3390/ijms23052412
Abstract: Transcription factors must scan genomic DNA, recognize the cognate sequence of their control element(s), and bind tightly to them. The DNA recognition process is primarily carried out by their DNA binding domains (DBD), which interact… read more here.
Keywords: cognate dna; dna; cognate; dna recognition ... See more keywords