Is There Any Evidence of Premature, Accentuated and Accelerated Aging Effects on Neurocognition in People Living with HIV? A Systematic Review
Sign Up to like & getrecommendations! Published in 2020 at "AIDS and Behavior"
DOI: 10.1007/s10461-020-03053-3
Abstract: Despite evidence of premature, accentuated and accelerated aging for some age-related conditions such as cardiovascular diseases in people living with HIV (PLHIV), the evidence for these abnormal patterns of aging on neurocognition remains unclear. Further,… read more here.
Keywords: age; hiv; premature; evidence ... See more keywords
Patterns of multi-domain cognitive aging in participants of the Long Life Family Study
Sign Up to like & getrecommendations! Published in 2020 at "GeroScience"
DOI: 10.1007/s11357-020-00202-3
Abstract: Maintaining good cognitive function at older age is important, but our knowledge of patterns and predictors of cognitive aging is still limited. We used Bayesian model-based clustering to group 5064 participants of the Long Life… read more here.
Keywords: change; participants long; long life; study ... See more keywords
Redefining Aging in HIV Infection Using Phenotypes
Sign Up to like & getrecommendations! Published in 2017 at "Current HIV/AIDS Reports"
DOI: 10.1007/s11904-017-0364-x
Abstract: Purpose of reviewThis article critically reviews the utility of “phenotypes” as behavioral descriptors in aging/HIV research that inform biological underpinnings and treatment development. We adopt a phenotypic redefinition of aging conceptualized within a broader context… read more here.
Keywords: hiv infection; research; aging hiv; cognitive aging ... See more keywords
Survey of the Arc Epigenetic Landscape in Normal Cognitive Aging
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01915-4
Abstract: Aging is accompanied by aberrant gene expression that ultimately affects brain plasticity and the capacity to form long-term memories. Immediate-early genes (IEGs) play an active role in these processes. Using a rat model of normal… read more here.
Keywords: epigenetic landscape; cognitive aging; expression; arc epigenetic ... See more keywords
How does decisional capacity evolve with normal cognitive aging: systematic review of the literature
Sign Up to like & getrecommendations! Published in 2019 at "European Geriatric Medicine"
DOI: 10.1007/s41999-019-00251-8
Abstract: Aim The complexity of decision-making involves many neurological functions and structures which are potentially altered by cognitive aging. Findings Our systematic review shows a decrease in processing speed in normal aging, usually compensated by experience.… read more here.
Keywords: decision; systematic review; cognitive aging; decision making ... See more keywords
The Mexican Cognitive Aging Ancillary Study (Mex-Cog): Study Design and Methods.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of gerontology and geriatrics"
DOI: 10.1016/j.archger.2020.104210
Abstract: OBJECTIVE Describe the protocol sample and instruments of the Cognitive Aging Ancillary Study in Mexico (Mex-Cog). The study performs an in-depth cognitive assessment in a subsample of older adults of the ongoing Mexican Health and… read more here.
Keywords: study; cog study; cognitive aging; mex cog ... See more keywords
Estrogens as neuroprotectants: Estrogenic actions in the context of cognitive aging and brain injury
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Neurobiology"
DOI: 10.1016/j.pneurobio.2015.12.008
Abstract: HIGHLIGHTSThe biological impacts of estrogen extend beyond the gonads to other bodily systems, including the brain and behavior.Conflicting preclinical and clinical data regarding actions of estrogens on the nervous system suggests that estrogen is a… read more here.
Keywords: aging brain; estrogen; cognitive aging; brain injury ... See more keywords
Alcohol use and cognitive aging in middle-aged men: The Vietnam Era Twin Study of Aging
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the International Neuropsychological Society"
DOI: 10.1017/s1355617722000169
Abstract: Abstract Objective: To determine associations of alcohol use with cognitive aging among middle-aged men. Method: 1,608 male twins (mean 57 years at baseline) participated in up to three visits over 12 years, from 2003–2007 to… read more here.
Keywords: cognitive aging; aged men; alcohol use; middle aged ... See more keywords
My parent, myself, or my child: whose education matters most for trajectories of cognitive aging in middle age?
Sign Up to like & getrecommendations! Published in 2023 at "American journal of epidemiology"
DOI: 10.1093/aje/kwad108
Abstract: The growing body of evidence linking intergenerational education and late-life cognitive decline is almost exclusively from high-income countries, despite rapid intergenerational changes in education in low- and middle-income countries (LMICs). We used data from the… read more here.
Keywords: verbal memory; cognitive aging; education; aging middle ... See more keywords
A Systematic Review for Functional Neuroimaging Studies of Cognitive Reserve Across the Cognitive Aging Spectrum
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Clinical Neuropsychology"
DOI: 10.1093/arclin/acx125
Abstract: Objective Cognitive reserve has been proposed to explain the discrepancy between clinical symptoms and the effects of aging or Alzheimer's pathology. Functional magnetic resonance imaging (fMRI) may help elucidate how neural reserve and compensation delay… read more here.
Keywords: aging spectrum; reserve; compensation; cognitive aging ... See more keywords
Age-Related Decline in the Topological Efficiency of the Brain Structural Connectome and Cognitive Aging.
Sign Up to like & getrecommendations! Published in 2020 at "Cerebral cortex"
DOI: 10.1093/cercor/bhaa066
Abstract: Brain disconnection model has been proposed as a possible neural mechanism for cognitive aging. However, the relationship between structural connectivity degeneration and cognitive decline with normal aging remains unclear. In the present study, using diffusion… read more here.
Keywords: brain structural; cognitive aging; decline; structural connectome ... See more keywords