Association of Sensory Impairments With Cognitive Decline and Depression Among Older Adults in China
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.14186
Abstract: Key Points Question Are visual and/or hearing impairments associated with cognitive decline and depression? Findings In this cross-sectional study of 18 038 participants aged 45 years or older in China, visual impairment was associated with worse… read more here.
Keywords: depression; decline depression; depression among; older adults ... See more keywords
Assessment of Plasma Amyloid-β42/40 and Cognitive Decline Among Community-Dwelling Older Adults
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DOI: 10.1001/jamanetworkopen.2020.28634
Abstract: Key Points Question Is plasma amyloid-β42/40 (Aβ42/40) associated with cognitive decline among community-dwelling older adults with memory concerns? Findings In this cohort study of 483 participants from a randomized clinical trial, low plasma Aβ42/40 ratio… read more here.
Keywords: plasma; decline; decline among; plasma amyloid ... See more keywords
Association of Cognitive Function Trajectories in Centenarians With Postmortem Neuropathology, Physical Health, and Other Risk Factors for Cognitive Decline
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.31654
Abstract: Key Points Question Are cognitively healthy centenarians resilient against further cognitive decline? Findings In this cohort study of 330 self-reported cognitively healthy centenarians, cognitive trajectories revealed only a slight decline in memory functioning, while other… read more here.
Keywords: association cognitive; risk factors; decline; factors cognitive ... See more keywords
Evaluation of Intensive vs Standard Blood Pressure Reduction and Association With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2021.34553
Abstract: Importance Optimal blood pressure (BP) targets for the prevention of cognitive impairment remain uncertain. Objective To explore the association of intensive (ie, lower than usual) BP reduction vs standard BP management with the incidence of… read more here.
Keywords: reduction; decline dementia; risk; dementia ... See more keywords
Examination of Neurofilament Light Chain Serum Concentrations, Physical Activity, and Cognitive Decline in Older Adults
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DOI: 10.1001/jamanetworkopen.2022.3596
Abstract: This cohort study uses data from the Chicago Health and Aging Project to examine associations between physical activity and cognitive decline by serum concentrations of neurofilament light (NfL) chain among older adults. read more here.
Keywords: older adults; neurofilament light; physical activity; activity cognitive ... See more keywords
A Blood-Based Biomarker of Cognitive Decline and Interaction With Lifestyle.
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DOI: 10.1001/jamanetworkopen.2022.3602
Abstract: Desai et al1 investigated whether engaging in physical activity moderated the association between concentrations of plasma neurofilament light chain (NfL) and cognitive function over time in adults aged 65 years or older who participated in… read more here.
Keywords: biomarker; physical activity; lifestyle factors; activity ... See more keywords
Associations Between Vascular Risk Factor Levels and Cognitive Decline Among Stroke Survivors
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DOI: 10.1001/jamanetworkopen.2023.13879
Abstract: Key Points Question Are higher blood pressure, glucose, and low-density lipoprotein cholesterol in stroke survivors associated with cognitive decline? Findings In this cohort study using a meta-analysis of individual participant data from 982 stroke survivors… read more here.
Keywords: decline; associations vascular; vascular risk; risk factor ... See more keywords
Trajectory of Cognitive Decline Before and After Stroke in 14 Population Cohorts
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DOI: 10.1001/jamanetworkopen.2024.37133
Abstract: This cohort study evaluates the trajectory of cognitive function before any stroke and after stroke in global cognition and in 4 cognitive domains. read more here.
Keywords: stroke population; stroke; cognitive decline; trajectory cognitive ... See more keywords
Alzheimer Disease Biomarkers and Subjective Cognitive Decline Among Hispanic and/or Latino Adults
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DOI: 10.1001/jamanetworkopen.2025.31038
Abstract: This cross-sectional study evaluates associations between plasma biomarkers of amyloid, tau, neuroaxonal damage, and glial activation with subjective cognitive decline in a heterogeneous cohort of Hispanic and/or Latino adults. read more here.
Keywords: cognitive decline; hispanic latino; subjective cognitive; latino adults ... See more keywords
Childhood Loneliness and Cognitive Decline and Dementia Risk in Middle-Aged and Older Adults
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DOI: 10.1001/jamanetworkopen.2025.31493
Abstract: Key Points Question Is childhood loneliness associated with cognitive decline and incident dementia? Findings In this cohort study of 13 592 participants, childhood loneliness was associated with faster cognitive decline and higher risk of incident dementia… read more here.
Keywords: cognitive decline; dementia risk; decline; childhood loneliness ... See more keywords
APOE4, Blood Neurodegenerative Biomarkers, and Cognitive Decline in Community-Dwelling Older Adults
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DOI: 10.1001/jamanetworkopen.2025.8903
Abstract: This cohort study investigates the interaction of APOE4 carrier status with the association between neurodegenerative biomarkers and rate of cognitive decline in older adults. read more here.
Keywords: apoe4 blood; cognitive decline; neurodegenerative biomarkers; blood neurodegenerative ... See more keywords