Association of Sensory Impairments With Cognitive Decline and Depression Among Older Adults in China
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.14186
Abstract: Key Points Question Are visual and/or hearing impairments associated with cognitive decline and depression? Findings In this cross-sectional study of 18 038 participants aged 45 years or older in China, visual impairment was associated with worse… read more here.
Keywords: depression; decline depression; depression among; older adults ... See more keywords
Assessment of Plasma Amyloid-β42/40 and Cognitive Decline Among Community-Dwelling Older Adults
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DOI: 10.1001/jamanetworkopen.2020.28634
Abstract: Key Points Question Is plasma amyloid-β42/40 (Aβ42/40) associated with cognitive decline among community-dwelling older adults with memory concerns? Findings In this cohort study of 483 participants from a randomized clinical trial, low plasma Aβ42/40 ratio… read more here.
Keywords: plasma; decline; decline among; plasma amyloid ... See more keywords
Association of Cognitive Function Trajectories in Centenarians With Postmortem Neuropathology, Physical Health, and Other Risk Factors for Cognitive Decline
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.31654
Abstract: Key Points Question Are cognitively healthy centenarians resilient against further cognitive decline? Findings In this cohort study of 330 self-reported cognitively healthy centenarians, cognitive trajectories revealed only a slight decline in memory functioning, while other… read more here.
Keywords: association cognitive; risk factors; decline; factors cognitive ... See more keywords
Evaluation of Intensive vs Standard Blood Pressure Reduction and Association With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2021.34553
Abstract: Importance Optimal blood pressure (BP) targets for the prevention of cognitive impairment remain uncertain. Objective To explore the association of intensive (ie, lower than usual) BP reduction vs standard BP management with the incidence of… read more here.
Keywords: reduction; decline dementia; risk; dementia ... See more keywords
Examination of Neurofilament Light Chain Serum Concentrations, Physical Activity, and Cognitive Decline in Older Adults
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DOI: 10.1001/jamanetworkopen.2022.3596
Abstract: This cohort study uses data from the Chicago Health and Aging Project to examine associations between physical activity and cognitive decline by serum concentrations of neurofilament light (NfL) chain among older adults. read more here.
Keywords: older adults; neurofilament light; physical activity; activity cognitive ... See more keywords
A Blood-Based Biomarker of Cognitive Decline and Interaction With Lifestyle.
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DOI: 10.1001/jamanetworkopen.2022.3602
Abstract: Desai et al1 investigated whether engaging in physical activity moderated the association between concentrations of plasma neurofilament light chain (NfL) and cognitive function over time in adults aged 65 years or older who participated in… read more here.
Keywords: biomarker; physical activity; lifestyle factors; activity ... See more keywords
Associations Between Vascular Risk Factor Levels and Cognitive Decline Among Stroke Survivors
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DOI: 10.1001/jamanetworkopen.2023.13879
Abstract: Key Points Question Are higher blood pressure, glucose, and low-density lipoprotein cholesterol in stroke survivors associated with cognitive decline? Findings In this cohort study using a meta-analysis of individual participant data from 982 stroke survivors… read more here.
Keywords: decline; associations vascular; vascular risk; risk factor ... See more keywords
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2021.5216
Abstract: Importance One characteristic histopathological event in Alzheimer disease (AD) is cerebral amyloid aggregation, which can be detected by biomarkers in cerebrospinal fluid (CSF) and on positron emission tomography (PET) scans. Prevalence estimates of amyloid pathology… read more here.
Keywords: amyloid abnormality; prevalence; dementia; subjective cognitive ... See more keywords
Association Between Consumption of Ultraprocessed Foods and Cognitive Decline.
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DOI: 10.1001/jamaneurol.2022.4397
Abstract: Importance Although consumption of ultraprocessed food has been linked to higher risk of cardiovascular disease, metabolic syndrome, and obesity, little is known about the association of consumption of ultraprocessed foods with cognitive decline. Objective To… read more here.
Keywords: decline; consumption; ultraprocessed food; consumption ultraprocessed ... See more keywords
Association of Hearing Aids and Cochlear Implants With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.4427
Abstract: Importance Hearing loss is associated with cognitive decline. However, it is unclear if hearing restorative devices may have a beneficial effect on cognition. Objective To evaluate the associations of hearing aids and cochlear implants with… read more here.
Keywords: decline; meta analysis; hearing loss; dementia ... See more keywords
Multi-domain interventions for the prevention of dementia and cognitive decline
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DOI: 10.1002/14651858.cd013572
Abstract: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:. To assess the effects of multi-domain interventions for the prevention of cognitive decline and dementia (a) in unselected populations and (b)… read more here.
Keywords: interventions prevention; decline; domain interventions; multi domain ... See more keywords