Born to Protect: Leveraging BDNF Against Cognitive Deficit in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2020 at "CNS Drugs"
DOI: 10.1007/s40263-020-00705-9
Abstract: Alzheimer’s disease is a chronic neurodegenerative devastating disorder affecting a high percentage of the population over 65 years of age and causing a relevant emotional, social, and economic burden. Clinically, it is characterized by a prominent… read more here.
Keywords: alzheimer disease; cognitive deficit; disease; brain derived ... See more keywords
Prophylactic effect of intravenous lidocaine against cognitive deficit after cardiac surgery: A PRISMA-compliant meta-analysis and trial sequential analysis
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030476
Abstract: Background: This study aimed at providing an updated evidence of the association between intraoperative lidocaine and risk of postcardiac surgery cognitive deficit. Methods: Randomized clinical trials (RCTs) investigating effects of intravenous lidocaine against cognitive deficit… read more here.
Keywords: cognitive deficit; analysis; intravenous lidocaine; deficit ... See more keywords
Differentiation of Cognitive Deficit Profiles in Multiple Sclerosis Patients: Latent Profile Analysis
Sign Up to like & getrecommendations! Published in 2019 at "Medical Principles and Practice"
DOI: 10.1159/000499312
Abstract: Objective: The purpose of this study was to ascertain whether the application of the Audio Recorded Cognitive Screen (ARCS) in cognitive functioning screening of persons with multiple sclerosis (MS) differentiates profiles of existing cognitive deficits… read more here.
Keywords: sclerosis; differentiation cognitive; profiles multiple; multiple sclerosis ... See more keywords
Deficiency of Endothelial Nitric Oxide Synthase (eNOS) Exacerbates Brain Damage and Cognitive Deficit in A Mouse Model of Vascular Dementia
Sign Up to like & getrecommendations! Published in 2021 at "Aging and Disease"
DOI: 10.14336/ad.2020.0523
Abstract: Vascular Dementia (VaD) accounts for nearly 20% of all cases of dementia. eNOS plays an important role in neurovascular remodeling, anti-inflammation, and cognitive functional recovery after stroke. In this study, we investigated whether eNOS regulates… read more here.
Keywords: cognitive deficit; damage; brain damage; damage cognitive ... See more keywords
Lacunar infarction aggravates the cognitive deficit in the elderly with white matter lesion
Sign Up to like & getrecommendations! Published in 2022 at "Open Life Sciences"
DOI: 10.1515/biol-2022-0027
Abstract: Abstract Cerebral white matter lesion (WML) and lacunar infarction (LI) were primary causes of cognitive deficit. Our study aimed to investigate the correlation between LI and cognitive deficit in the elderly with WML. A total… read more here.
Keywords: wml; white matter; wmls; deficit ... See more keywords
White Matter Abnormalities and Cognitive Deficit After Mild Traumatic Brain Injury: Comparing DTI, DKI, and NODDI
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.803066
Abstract: White matter (WM) disruption is an important determinant of cognitive impairment after mild traumatic brain injury (mTBI), but traditional diffusion tensor imaging (DTI) shows some limitations in assessing WM damage. Diffusion kurtosis imaging (DKI) and… read more here.
Keywords: diffusion; white matter; mild traumatic; cognitive deficit ... See more keywords
Associations Among Suicidal Ideation, White Matter Integrity and Cognitive Deficit in First-Episode Schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2018.00391
Abstract: Objective: The study was aimed to investigate the possible associations among suicidal ideation, brain white matter (WM) integrity and cognitive deficit in first-episode schizophrenia (FES) using diffusion tensor imaging. Methods: The sample contained 18 FES… read more here.
Keywords: ideation; suicidal ideation; integrity; cognitive deficit ... See more keywords
Association of Cognitive Deficit with Glutamate and Insulin Signaling in a Rat Model of Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11030683
Abstract: Cognitive deficit is a frequent non-motor symptom in Parkinson’s disease (PD) with an unclear pathogenesis. Recent research indicates possible involvement of insulin resistance and glutamate excitotoxicity in PD development. We investigated cognitive performance and the… read more here.
Keywords: glutamate insulin; cognitive deficit; rat model; insulin signaling ... See more keywords
Gait Performance as an Indicator of Cognitive Deficit in Older People
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph18073428
Abstract: Background: The purpose of this study was to analyze which gait variables are the best for detecting cognitive impairment and to determine if age and gender can influence gait variations in older people. Methods: 65… read more here.
Keywords: older people; gait performance; performance indicator; gait ... See more keywords
A Prospective Study of Longitudinal Risks of Cognitive Deficit for People Undergoing Glioblastoma Surgery Using a Tablet Computer Cognition Testing Battery: Towards Personalized Understanding of Risks to Cognitive Function
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13020278
Abstract: Glioblastoma and the surgery to remove it pose high risks to the cognitive function of patients. Little reliable data exist about these risks, especially postoperatively before radiotherapy. We hypothesized that cognitive deficit risks detected before… read more here.
Keywords: cognitive function; surgery; cognitive deficit; glioblastoma surgery ... See more keywords
Kaempferol attenuates cognitive deficit via regulating oxidative stress and neuroinflammation in an ovariectomized rat model of sporadic dementia
Sign Up to like & getrecommendations! Published in 2018 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.238714
Abstract: Alzheimer's disease (AD) is associated with oxidative stress, and ultimately results in cognitive deficit. Despite existing literature on the pathophysiology of AD, there is currently no cure for AD. The present study investigated the effects… read more here.
Keywords: stz; kmp; ovx stz; cognitive deficit ... See more keywords