Cognitive dysfunction 1 year after COVID‐19: evidence from eye tracking
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DOI: 10.1002/acn3.51675
Abstract: Increasing evidence suggests persistent cognitive dysfunction after COVID‐19. In this cross‐sectional study, frontal lobe function was assessed 12 months after the acute phase of the disease, using tailored eye tracking assessments. Individuals who recovered from COVID‐19… read more here.
Keywords: cognitive dysfunction; covid; evidence; eye tracking ... See more keywords
Intranasally Delivered Echinacoside Micelles Modulate Mitochondrial Fusion Against Postoperative Cognitive Dysfunction
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DOI: 10.1002/adfm.202505499
Abstract: The disruption of mitochondrial homeostasis in neurons accounts for the onset and progression of postoperative cognitive dysfunction (POCD). Echinacoside (ECH) can facilitate mitochondrial fusion to mediate neuroprotection, but its therapeutic efficacy is greatly limited by… read more here.
Keywords: intranasally delivered; mitochondrial fusion; fusion; cognitive dysfunction ... See more keywords
Multidomain cognitive dysfunction after minor stroke suggests generalized disruption of cognitive networks
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DOI: 10.1002/brb3.2571
Abstract: Although small strokes typically result in “good” functional outcomes, significant cognitive impairment can occur. This longitudinal study examined a cohort of patients with minor stroke to determine the pattern of deficits, evolution over time, and… read more here.
Keywords: multidomain cognitive; stroke suggests; cognitive dysfunction; suggests generalized ... See more keywords
Influence of dexmedetomidine on postoperative cognitive dysfunction in the elderly: A meta‐analysis of randomized controlled trials
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DOI: 10.1002/brb3.2665
Abstract: Dexmedetomidine (Dex) is suggested to be neuroprotective. However, influence of Dex on postoperative cognitive dysfunction (POCD) in the elderly remains unknown. read more here.
Keywords: cognitive dysfunction; postoperative cognitive; influence dexmedetomidine;
Exogenous recombinant Hsp70 attenuates sevoflurane anesthesia‐induced cognitive dysfunction in aged mice
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DOI: 10.1002/brb3.2861
Abstract: Postoperative cognitive dysfunction (POCD) is a severe postoperative neurological sequela in elderly patients, and there is currently no standard treatment for POCD. In this study, whether recombinant human heat shock protein 70 (rHsp70) could alleviate… read more here.
Keywords: cognitive dysfunction; induced cognitive; aged mice; exogenous recombinant ... See more keywords
Obsessive-compulsive disorder: Etiology, neuropathology, and cognitive dysfunction.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3000
Abstract: BACKGROUND This review provides an overview of obsessive-compulsive disorder (OCD) symptoms, including the four partially distinct subtypes of the disorder, current diagnostic criteria, and common comorbidities. Critically, it focuses on the etiology of OCD, including… read more here.
Keywords: cognitive dysfunction; compulsive disorder; etiology; obsessive compulsive ... See more keywords
Ononin, a Natural Isoflavone Glycoside, Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Regulating Neuroinflammation and Oxidative Stress
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DOI: 10.1002/brb3.70952
Abstract: Postoperative cognitive dysfunction (POCD) is a serious neurological complication that currently lacks effective clinical prevention and treatment. Ononin, a natural isoflavone glycoside, has been confirmed to exhibit potent neuroprotective effects. This study aimed to investigate… read more here.
Keywords: ononin natural; natural isoflavone; cognitive dysfunction; postoperative cognitive ... See more keywords
Remote assessment of cognitive dysfunction in hematologic malignancies using web‐based neuropsychological testing
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DOI: 10.1002/cam4.5331
Abstract: Cognitive impairment is a frequent adverse effect of cancer and its therapies. As neuropsychological assessment is not often standard of care for patients with non‐CNS disease, efficient, practical assessment tools are required to track cognition… read more here.
Keywords: assessment cognitive; web based; dysfunction hematologic; cognitive dysfunction ... See more keywords
Carnosol alleviates sevoflurane‑induced cognitive dysfunction by mediating NF‑κB pathway in aged rats
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DOI: 10.1002/ddr.21963
Abstract: Postoperative Cognitive Dysfunction (POCD) is a neurological disorder of unconsciousness due to cognitive regression after surgical anesthesia. However, the specific mechanism has not yet been clarified. Sevoflurane (SEV) is one of the most commonly used… read more here.
Keywords: cognitive dysfunction; effects carnosol; aged rats; sev mediated ... See more keywords
The Role of Iron Homeostasis Imbalance in T2DM‐Associated Cognitive Dysfunction: A Prospective Cohort Study Utilizing Quantitative Susceptibility Mapping
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DOI: 10.1002/hbm.70263
Abstract: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that significantly impacts cognitive health. Although the vascular complications of T2DM have been extensively studied, research on brain iron deposition in T2DM remains scarce, and… read more here.
Keywords: t2dm; susceptibility; iron; cognitive dysfunction ... See more keywords
Effects of dexmedetomidine on cognitive dysfunction and neuroinflammation via the HDAC2/HIF‐1α/PFKFB3 axis in a murine model of postoperative cognitive dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23044
Abstract: Inhibition of histone deacetylase (HDAC) may be a useful approach in the treatment of disorders characterized by cognitive dysfunction. Dexmedetomidine (DEX), an α2‐adrenoceptor (α2‐AR) agonist, has demonstrated neuroprotective effects. Here, we attempted to investigate the… read more here.
Keywords: cognitive dysfunction; hif pfkfb3; dysfunction; hdac2 ... See more keywords