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   Articles with "cognitive impairment" as a keyword



Deprescribing Education vs Usual Care for Patients With Cognitive Impairment and Primary Care Clinicians

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recommendations! Published in 2022 at "JAMA Internal Medicine"

DOI: 10.1001/jamainternmed.2022.0502

Abstract: Key Points Question Can increasing awareness about deprescribing prior to primary care visits reduce the use of potentially inappropriate long-term medications for individuals with cognitive impairment? Findings In this pragmatic cluster randomized clinical trial of… read more here.

Keywords: cognitive impairment; care clinicians; care; primary care ... See more keywords

Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment

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recommendations! Published in 2019 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2019.10319

Abstract: Key Points Question Is alcohol consumption associated with the risk of dementia and cognitive decline in older adults with or without mild cognitive impairment? Findings In this cohort study of 3021 participants aged 72 years… read more here.

Keywords: risk dementia; alcohol consumption; cognitive impairment; without mild ... See more keywords
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Association of β-Amyloid Burden With Sleep Dysfunction and Cognitive Impairment in Elderly Individuals With Cognitive Disorders

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recommendations! Published in 2019 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2019.13383

Abstract: Key Points Question Is β-amyloid deposition in the brain associated with sleep dysfunction and cognition in elderly individuals with cognitive disorders? Findings In this survey study of 52 participants aged 65 years and older, β-amyloid… read more here.

Keywords: elderly individuals; cognitive impairment; cognitive disorders; individuals cognitive ... See more keywords
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Comparative Effectiveness of Behavioral Interventions on Quality of Life for Older Adults With Mild Cognitive Impairment

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recommendations! Published in 2019 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2019.3016

Abstract: This cluster randomized, multicomponent comparative effectiveness trial compares the incremental effects of combinations of 5 behavioral interventions on outcomes of highest importance to patients with mild cognitive impairment. read more here.

Keywords: effectiveness behavioral; cognitive impairment; behavioral interventions; comparative effectiveness ... See more keywords

Association of Modifiable Lifestyle Factors With Cortical Amyloid Burden and Cerebral Glucose Metabolism in Older Adults With Mild Cognitive Impairment

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recommendations! Published in 2020 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2020.5719

Abstract: Key Points Question Are modifiable lifestyle factors associated with cortical amyloid burden or cerebral glucose metabolism in older adults with mild cognitive impairment? Findings This cohort study included 118 older adults with mild cognitive impairment… read more here.

Keywords: adults mild; cognitive impairment; impairment; cerebral glucose ... See more keywords

Risk of Mild Cognitive Impairment or Probable Dementia in New Users of Angiotensin II Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.20680

Abstract: Key Points Question Is initiation of angiotensin II receptor blockers (ARBs), compared with angiotensin-converting enzyme inhibitors (ACEIs), associated with a reduced risk of cognitive impairment, after controlling for potential pretreatment confounders? Findings This active-comparator, new-user… read more here.

Keywords: new users; angiotensin receptor; cognitive impairment; receptor blockers ... See more keywords

In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization

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recommendations! Published in 2024 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2024.19640

Abstract: Key Points Question Among older adults (aged 60 years or older) hospitalized for COVID-19, is in-hospital delirium associated with functional disability and cognitive impairment over the 6 months after discharge? Findings In this cohort study… read more here.

Keywords: cognitive impairment; hospital delirium; disability cognitive;

Development and Validation of a Tool to Predict Onset of Mild Cognitive Impairment and Alzheimer Dementia

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recommendations! Published in 2025 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2024.53756

Abstract: Key Points Question Can the age at onset of mild cognitive impairment (MCI) and Alzheimer dementia (AD) be predicted using a statistical modeling approach? Findings In this prognostic study that used data from 3787 patients,… read more here.

Keywords: onset mild; dementia; cognitive impairment; alzheimer dementia ... See more keywords

Association of Initial β-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment.

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recommendations! Published in 2020 at "JAMA neurology"

DOI: 10.1001/jamaneurol.2020.3921

Abstract: Importance Tau accumulation in Alzheimer disease (AD) is closely associated with cognitive impairment. Quantitating tau accumulation by positron emission tomography (PET) will be a useful outcome measure for future clinical trials in the AD spectrum.… read more here.

Keywords: accumulation; pet; tau accumulation; suvr units ... See more keywords

Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment.

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recommendations! Published in 2022 at "JAMA neurology"

DOI: 10.1001/jamaneurol.2022.2379

Abstract: Importance National Institute on Aging-Alzheimer's Association (NIA-AA) workgroups have proposed biological research criteria intended to identify individuals with preclinical Alzheimer disease (AD). Objective To assess the clinical value of these biological criteria to identify older… read more here.

Keywords: near term; tau; without cognitive; alzheimer disease ... See more keywords

Racial and Ethnic Differences in Amyloid PET Positivity in Individuals With Mild Cognitive Impairment or Dementia

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recommendations! Published in 2022 at "JAMA Neurology"

DOI: 10.1001/jamaneurol.2022.3157

Abstract: Key Points Question Do amyloid positron emission tomography (PET) positivity rates differ across racial and ethnic groups with mild cognitive impairment (MCI) or dementia? Findings In this cohort study of 17 107 Medicare beneficiaries with MCI… read more here.

Keywords: mild cognitive; pet positivity; racial ethnic; cognitive impairment ... See more keywords