Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus
Sign Up to like & getrecommendations! Published in 2021 at "Redox Biology"
DOI: 10.1016/j.redox.2021.101973
Abstract: Persistent cognitive and mood dysfunction is the primary CNS symptom in veterans afflicted with Gulf War Illness (GWI). This study investigated the efficacy of melatonin (MEL) for improving cognitive and mood function with antioxidant, antiinflammatory,… read more here.
Keywords: hippocampus; mel; model chronic; cognitive mood ... See more keywords
Cognitive and mood side effects of lower urinary tract medication
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DOI: 10.1080/14740338.2019.1652269
Abstract: ABSTRACT Introduction: Muscarinic receptor antagonists, 5α-reductase inhibitors and α1-adrenoceptor antagonists are frequently used drug classes for the treatment of lower urinary tract symptoms including those of overactive bladder syndrome and benign prostatic enlargement/benign prostatic obstruction.… read more here.
Keywords: lower urinary; mood side; urinary tract; cognitive mood ... See more keywords
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis
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DOI: 10.1186/s40779-024-00563-2
Abstract: Chronic Gulf War Illness (GWI) is characterized by cognitive and mood impairments, as well as persistent neuroinflammation and oxidative stress. This study aimed to investigate the efficacy of Epidiolex®, a Food and Drug Administration (FDA)-approved… read more here.
Keywords: gwi; gulf war; cognitive mood; war illness ... See more keywords
Prevalence of Cognitive and Mood-Related Symptoms in a Large Cohort of Perimenopausal and Menopausal Women
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DOI: 10.1192/bjo.2024.497
Abstract: Aims Current NICE guidance (NG23) lists hot flushes and night sweats as the most common symptoms associated with the perimenopause and menopause. Consequently, many clinicians, and the public in general, often associate menopause primarily with… read more here.
Keywords: menopausal women; mood; cognitive mood; related symptoms ... See more keywords