Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24271
Abstract: Traumatic brain injury (TBI) results in cognitive impairment, which can be long‐lasting after moderate to severe TBI. Currently, there are no FDA‐approved therapeutics to treat the devastating consequences of TBI and improve recovery. This study… read more here.
Keywords: mitochondrial bioenergetics; traumatic brain; cognitive outcome; post injury ... See more keywords
Subgroup analysis of seizure and cognitive outcome after vagal nerve stimulator implantation in children
Sign Up to like & getrecommendations! Published in 2020 at "Child's Nervous System"
DOI: 10.1007/s00381-020-04628-0
Abstract: Objective Vagal nerve stimulator (VNS) implantation at an early age seems to lead to improved quality of life and cognitive outcome. The aim of this analysis is to evaluate whether specific patient or seizure characteristics… read more here.
Keywords: outcome; seizure; cognitive outcome; implantation ... See more keywords
Magnetic resonance imaging markers reflect cognitive outcome after rehabilitation in children with acquired brain injury.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2020.108963
Abstract: PURPOSE To test markers from conventional and diffusion Magnetic Resonance Imaging (MRI) as possible predictors of cognitive outcome following rehabilitation therapy in children with acquired brain injury (ABI). METHODS Twenty-one children (10 boys, mean age… read more here.
Keywords: rehabilitation; cognitive outcome; injury; brain injury ... See more keywords
Cognitive Outcome After Epilepsy Surgery in Children.
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in pediatric neurology"
DOI: 10.1016/j.spen.2017.10.010
Abstract: Cognitive dysfunction in children with epilepsy is primarily contributed by etiology, seizures, frequency of interictal epileptiform discharges, and adverse effects of antiepileptic drugs. The direct effect of epilepsy surgery on cognitive outcome depends on two… read more here.
Keywords: epilepsy surgery; cognitive outcome; surgery; epileptogenic zone ... See more keywords
Determining factors of the cognitive outcome in early treated PKU: A study of 39 pediatric patients
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics and Metabolism Reports"
DOI: 10.1016/j.ymgmr.2019.100498
Abstract: Phenylketonuria (PKU) is a disorder of phenylalanine metabolism, characterized by a neurotoxic phenylalanine (Phe) accumulation, and treatable with a life-long Phe-restricted diet. Though early and continuously treated PKU (ETPKU) patients exhibit normal IQ, their cognitive… read more here.
Keywords: determining factors; treated pku; cognitive outcome; metabolic control ... See more keywords
Do we have scientific evidence about the effect of hypoxaemia on cognitive outcome in adult patients with severe acute respiratory failure?
Sign Up to like & getrecommendations! Published in 2018 at "Upsala Journal of Medical Sciences"
DOI: 10.1080/03009734.2018.1433255
Abstract: Do we have scientific evidence about the effect of hypoxaemia on cognitive outcome in adult patients with severe acute respiratory failure? read more here.
Keywords: evidence effect; hypoxaemia cognitive; scientific evidence; effect hypoxaemia ... See more keywords
Cognitive outcome following complicated mild Traumatic Brain Injury: A literature review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurotrauma"
DOI: 10.1089/neu.2023.0020
Abstract: Cognitive outcome for mild TBI with positive brain imaging (complicated MTBI) was compared with that for mild TBI with normal imaging (uncomplicated MTBI) and moderate to severe TBI using meta-analysis. Twenty-three studies utilising objective neurocognitive… read more here.
Keywords: injury; meta analysis; cognitive outcome; complicated mtbi ... See more keywords
1139 Sleep Disturbances In Chronic Stroke Patients: Emotional And Cognitive Impact
Sign Up to like & getrecommendations! Published in 2020 at "Sleep"
DOI: 10.1093/sleep/zsaa056.1133
Abstract: The objective was to investigate the impact of sleep-wake disturbances (SWD) on cognition and quality of life in the post-acute phase of stroke. Adult stroke (n=92) patients were assessed for SWD via overnight polysomnography. The… read more here.
Keywords: impact; time; cognitive outcome; ahi ... See more keywords
Serum‐neuroproteins, near‐infrared spectroscopy, and cognitive outcome after beach‐chair shoulder surgery: Observational cohort study analyses
Sign Up to like & getrecommendations! Published in 2020 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.13691
Abstract: Cerebral hypoxia may occur during surgery but currently used cerebral oxygenation saturation (rSO2) monitors remain controversial with respect to improving clinical outcome. Novel neuroprotein biomarkers are potentially released into systemic circulation and combined with near‐infrared… read more here.
Keywords: infrared spectroscopy; outcome; beach chair; near infrared ... See more keywords
Influence of contraindicated medication use on cognitive outcome in Dravet syndrome and age at first afebrile seizure as a clinical predictor in SCN1A‐related seizure phenotypes
Sign Up to like & getrecommendations! Published in 2018 at "Epilepsia"
DOI: 10.1111/epi.14191
Abstract: Pathogenic variants in SCN1A can give rise to extremely variable disease severities that may be indistinguishable at their first presentation. We aim to find clinical features that can help predict the evolution of seizures into… read more here.
Keywords: contraindicated medication; cognitive outcome; dravet syndrome; seizure ... See more keywords
Cognitive Outcome 1 Year After Mild Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000200041
Abstract: Background and Objectives The objectives of this study were to develop and establish concurrent validity of a clinically relevant definition of poor cognitive outcome 1 year after mild traumatic brain injury (mTBI), to compare baseline… read more here.
Keywords: poor year; outcome; cognitive outcome; outcome year ... See more keywords