Psychometric approaches to defining cognitive phenotypes in the Old Order Amish
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5903
Abstract: Memory and cognitive problems are central to the diagnosis of Alzheimer's disease (AD). Psychometric approaches to defining phenotypes can aid in identify genetic variants associated with AD. However, these approaches have mostly been limited to… read more here.
Keywords: phenotypes old; approaches defining; defining cognitive; cognitive phenotypes ... See more keywords
Cognitive Phenotypes for Biomarker Identification in Mental Illness: Forward and Reverse Translation.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2018_50
Abstract: Psychiatric illness has been acknowledged for as long as people were able to describe behavioral abnormalities in the general population. In modern times, these descriptions have been codified and continuously updated into manuals by which… read more here.
Keywords: illness; biomarker identification; identification mental; cognitive phenotypes ... See more keywords
Predominant cognitive phenotypes in multiple sclerosis: Insights from patient-centered outcomes.
Sign Up to like & getrecommendations! Published in 2021 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2021.102919
Abstract: BACKGROUND Since combining information from different domains could be useful to increase prediction accuracy over and above what can be achieved at the level of single category of markers, this study aimed to identify distinct… read more here.
Keywords: cognitive phenotypes; memory language; multiple sclerosis; predominant cognitive ... See more keywords
Cognitive phenotypes in late-life depression
Sign Up to like & getrecommendations! Published in 2022 at "International Psychogeriatrics"
DOI: 10.1017/s1041610222000515
Abstract: OBJECTIVE To identify cognitive phenotypes in late-life depression (LLD) and describe relationships with sociodemographic and clinical characteristics. DESIGN Observational cohort study. SETTING Baseline data from participants recruited via clinical referrals and community advertisements who enrolled… read more here.
Keywords: late life; phenotypes late; life depression; cognitive phenotypes ... See more keywords
Cognitive Phenotypes of Older Adults with Subjective Cognitive Decline and Amnestic Mild Cognitive Impairment: The Czech Brain Aging Study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the International Neuropsychological Society"
DOI: 10.1017/s1355617720001046
Abstract: Abstract Objective: To compare cognitive phenotypes of participants with subjective cognitive decline (SCD) and amnestic mild cognitive impairment (aMCI), estimate progression to MCI/dementia by phenotype and assess classification error with machine learning. Method: Dataset consisted… read more here.
Keywords: mild cognitive; impairment; cognitive phenotypes; amnestic mild ... See more keywords
Cognitive Phenotypes in Frontal Lobe Epilepsy.
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17260
Abstract: OBJECTIVE Neuropsychological profiles are heterogeneous both across and within epilepsy syndromes, but especially in frontal lobe epilepsy (FLE), which has complex semiology and epileptogenicity. This study aimed to characterize the cognitive heterogeneity within FLE by… read more here.
Keywords: frontal lobe; lobe epilepsy; impairment; epilepsy ... See more keywords
Perspectives on Cognitive Phenotypes and Models of Vascular Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Arteriosclerosis, thrombosis, and vascular biology"
DOI: 10.1161/atvbaha.122.317395
Abstract: Clinical investigations have established that vascular-associated medical conditions are significant risk factors for various kinds of dementia. And yet, we are unable to associate certain types of vascular deficiencies with specific cognitive impairments. The reasons… read more here.
Keywords: perspectives cognitive; disease; phenotypes models; cognitive phenotypes ... See more keywords
Parkinson's Disease Cognitive Phenotypes Show Unique Clock Drawing Features when Measured with Digital Technology.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Parkinson's disease"
DOI: 10.3233/jpd-202399
Abstract: BACKGROUND A companion paper (Crowley et al., 2020) reports on the neuroimaging and neuropsychological profiles of statistically determined idiopathic non-dementia Parkinson's disease (PD). OBJECTIVE The current investigation sought to further examine subtle behavioral clock drawing… read more here.
Keywords: parkinson disease; clock; cognitive phenotypes; clock drawing ... See more keywords
Identifying different cognitive phenotypes and their relationship with disability in neuromyelitis optica spectrum disorder
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.958441
Abstract: Background The existence, frequency, and features of cognitive impairment (CI) in patients with neuromyelitis optica spectrum disorder (NMOSD) are still debated. A precise classification and characterization of cognitive phenotypes in patients with NMOSD are lacking.… read more here.
Keywords: neuromyelitis optica; optica spectrum; disability; spectrum disorder ... See more keywords