Assessment of Demographic, Genetic, and Imaging Variables Associated With Brain Resilience and Cognitive Resilience to Pathological Tau in Patients With Alzheimer Disease
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2019.5154
Abstract: This cross-sectional, longitudinal study of amyloid-β–positive individuals with mild cognitive impairment or Alzheimer disease dementia examines the factors associated with interindividual differences in brain and cognitive resilience to tau positron emission tomography load and to… read more here.
Keywords: tau; alzheimer disease; resilience; cognitive resilience ... See more keywords
Dendritic spines provide cognitive resilience against Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.25049
Abstract: Neuroimaging and other biomarker assays suggest that the pathological processes of Alzheimer's disease (AD) begin years prior to clinical dementia onset. However, some 30 to 50% of older individuals who harbor AD pathology do not… read more here.
Keywords: alzheimer disease; cognitive resilience; dendritic spines; pathology ... See more keywords
Non-Alzheimer’s contributions to dementia and cognitive resilience in The 90+ Study
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neuropathologica"
DOI: 10.1007/s00401-018-1872-5
Abstract: The diagnosis of Alzheimer’s disease (AD) in the oldest-old is complicated by the increasing prevalence of age-related neurofibrillary tangles, plaques and non-AD pathologies such as cerebrovascular disease (CVD), hippocampal sclerosis (HS), aging-related tau astrogliopathy (ARTAG),… read more here.
Keywords: tdp lewy; dementia; pathology; cognitive resilience ... See more keywords
The metabolic brain signature of cognitive resilience in the 80+: beyond Alzheimer pathologies
Sign Up to like & getrecommendations! Published in 2019 at "Brain"
DOI: 10.1093/brain/awz037
Abstract: Research into cognitive resilience imaging markers may help determine the clinical significance of Alzheimer's disease pathology among older adults over 80 years (80+). In this study, we aimed to identify a fluorodeoxyglucose (FDG)-PET based imaging… read more here.
Keywords: resilience signature; disease; fdg pet; resilience ... See more keywords
Well-Being and Cognitive Resilience to Dementia-Related Neuropathology
Sign Up to like & getrecommendations! Published in 2022 at "Psychological Science"
DOI: 10.1177/09567976221119828
Abstract: Not all older adults with dementia-related neuropathology in their brains experience cognitive decline or impairment. Instead, some people maintain relatively normal cognitive functioning despite neuropathologic burden, a phenomenon called cognitive resilience. Using a longitudinal, epidemiological,… read more here.
Keywords: resilience; related neuropathology; cognitive resilience; well cognitive ... See more keywords
Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000200017
Abstract: Background and Objectives Cognitive resilience is a well-recognized concept, but knowledge gaps about its underlying mechanisms have made it difficult to develop instruments that identify older adults with high or low resilience. We tested whether… read more here.
Keywords: resilience; decline; index; older adults ... See more keywords
Effects of a Multi-Suckling System Combined With Enriched Housing Post-Weaning on Response and Cognitive Resilience to Isolation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.868149
Abstract: Improving welfare is still a critical issue in pig husbandry. Upgrades of the housing environment seem to be a promising solution to optimise resilience as a whole, and therefore improve animal welfare. The objective of… read more here.
Keywords: housing; system; resilience; welfare ... See more keywords