Effects of physical exercise on executive function in cognitively healthy older adults: A systematic review and meta-analysis of randomized controlled trials: Physical exercise for executive function.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of nursing studies"
DOI: 10.1016/j.ijnurstu.2020.103810
Abstract: OBJECTIVE To assess the effect of physical exercise interventions on executive function in cognitively healthy adults aged 60 years and older. METHODS Four electronic databases, the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Web… read more here.
Keywords: exercise; physical exercise; executive function; cognitively healthy ... See more keywords
β-amyloid pathology and hippocampal atrophy are independently associated with memory function in cognitively healthy elderly
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-47638-y
Abstract: The independent effects of different brain pathologies on age-dependent cognitive decline are unclear. We examined this in 300 cognitively unimpaired elderly individuals from the BioFINDER study. Using cognition as outcome we studied the effects of… read more here.
Keywords: cognitively healthy; healthy elderly; associated memory; pathology ... See more keywords
Disrupted brain functional connectivity as early signature in cognitively healthy individuals with pathological CSF amyloid/tau
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06673-w
Abstract: Alterations in functional connectivity (FC) have been observed in individuals with Alzheimer’s disease (AD) with elevated amyloid (Aβ) and tau. However, it is not yet known whether directed FC is already influenced by Aβ and… read more here.
Keywords: cognitively healthy; tau; csf; connectivity ... See more keywords
Limited English proficiency inhibits auditory verbal learning in cognitively healthy young adults – exploring culturally responsive diagnostic and educational safeguards
Sign Up to like & getrecommendations! Published in 2022 at "Applied Neuropsychology: Child"
DOI: 10.1080/21622965.2022.2034628
Abstract: Abstract This study was designed to examine the effect of limited English proficiency (LEP) on the Hopkins Verbal Learning Test-Revised (HVLT-R). The HVLT-R was administered to 28 undergraduate student volunteers. Half were native speakers of… read more here.
Keywords: auditory verbal; limited english; english proficiency; verbal learning ... See more keywords
Longitudinal associations between C-reactive protein and cognitive performance in normative cognitive ageing and dementia.
Sign Up to like & getrecommendations! Published in 2021 at "Age and ageing"
DOI: 10.1093/ageing/afab152
Abstract: BACKGROUND systemic inflammation appears to play an important role in the pathogenesis and expression of Alzheimer's disease and other dementias. Previous research has found that elevated levels of serum C-reactive protein (CRP) is associated with… read more here.
Keywords: cognitively healthy; longitudinal associations; dementia; reactive protein ... See more keywords
Clinical and MRI Correlates of β‐Amyloid Load Inconsistent With Its Presumed Neurotoxicity in Cognitively Healthy Ageing
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.70241
Abstract: Cognitively healthy ageing and its conceptual counterpart, dementia, have long garnered much interest in the research community, the broader public and regulatory bodies alike. Although β‐amyloid deposition is widely regarded as the principal neuropathological hallmark… read more here.
Keywords: neurotoxicity; amyloid load; cognitively healthy; mri ... See more keywords
Dementia Patients Are More Sedentary and Less Physically Active than Age- and Sex-Matched Cognitively Healthy Older Adults
Sign Up to like & getrecommendations! Published in 2018 at "Dementia and Geriatric Cognitive Disorders"
DOI: 10.1159/000491995
Abstract: Aims: The aim of this study was to examine physical activity and sedentary behaviour characteristics of ambulatory and community-dwelling patients with dementia compared to cognitively healthy age-, sex- and weight-matched controls. Methods: In this cross-sectional… read more here.
Keywords: cognitively healthy; age; age sex; dementia patients ... See more keywords
Longitudinal online weekly reports of non-cognitive symptoms and events can differentiate incident mild cognitive impairment from stable cognitively healthy older adults
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Alzheimer's Disease"
DOI: 10.1177/13872877251376524
Abstract: Background Changes in noncognitive symptoms such as mood, loneliness, pain, and need for assistance may be potential early markers of mild cognitive impairment (MCI) and Alzheimer's disease and related disorders (ADRD) in older adults. These… read more here.
Keywords: cognitive impairment; cognitively healthy; older adults; mild cognitive ... See more keywords
Self-reported oral health in the Dutch 100-plus Study of cognitively healthy centenarians: an observational cohort study
Sign Up to like & getrecommendations! Published in 2019 at "BMC Geriatrics"
DOI: 10.1186/s12877-019-1358-x
Abstract: BackgroundDue to improved healthcare, more people reach extreme ages. Oral health in the oldest-old has thus far been poorly described. Here, we investigated self-reported oral health factors, use of professional oral health care, and associations… read more here.
Keywords: cognitively healthy; health care; oral health; health ... See more keywords
Associations Between Repetitive Negative Thinking and Objective and Subjective Sleep Health in Cognitively Healthy Older Adults
Sign Up to like & getrecommendations! Published in 2024 at "Nature and Science of Sleep"
DOI: 10.2147/nss.s441509
Abstract: Objective Poor sleep and high levels of repetitive negative thinking (RNT), including future-directed (ie, worry) and past-directed (ie, brooding) negative thoughts, have been associated with markers of dementia risk. The relationship between RNT and sleep… read more here.
Keywords: subjective sleep; cognitively healthy; healthy older; repetitive negative ... See more keywords
Automated Volumetric Software in Dementia: Help or Hindrance to the Neuroradiologist?
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a8406
Abstract: This study aimed to determine if a quantitative volumetric report, compared with visual assessment alone, would improve the neuroradiologist's ability to correctly diagnose AD, FTD, or cognitively normal patients. The authors found that the brain… read more here.
Keywords: dementia; report; cognitively healthy; accuracy ... See more keywords