Articles with "cohesin loss" as a keyword



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Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs

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Published in 2019 at "Current Biology"

DOI: 10.1016/j.cub.2019.09.006

Abstract: Summary Chromosome segregation errors during female meiosis are a leading cause of pregnancy loss and human infertility. The segregation of chromosomes is driven by interactions between spindle microtubules and kinetochores. Kinetochores in mammalian oocytes are… read more here.

Keywords: cohesin loss; kinetochore; age; fragmentation ... See more keywords