Articles with "coil domains" as a keyword



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Transmembrane and coiled-coil domains 3 is a diagnostic biomarker for predicting immune checkpoint blockade efficacy in hepatocellular carcinoma

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.1006357

Abstract: Liver hepatocellular carcinoma (LIHC) is a malignancy with a high mortality and morbidity rate worldwide. However, the pathogenesis of LIHC has still not been thoroughly studied. Transmembrane and coiled-coil domains 3 (TMCO3) encodes a monovalent… read more here.

Keywords: hepatocellular carcinoma; tmco3; transmembrane coiled; coiled coil ... See more keywords
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The 2β Splice Variation Alters the Structure and Function of the Stromal Interaction Molecule Coiled-Coil Domains

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Published in 2018 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms19113316

Abstract: Stromal interaction molecule (STIM)-1 and -2 regulate agonist-induced and basal cytosolic calcium (Ca2+) levels after oligomerization and translocation to endoplasmic reticulum (ER)-plasma membrane (PM) junctions. At these junctions, the STIM cytosolic coiled-coil (CC) domains couple… read more here.

Keywords: coiled coil; coil domains; interaction molecule; stromal interaction ... See more keywords