Co-assembled Coiled-Coil Peptide Nanotubes with Enhanced Stability and Metal-Dependent Cargo Loading
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01669
Abstract: Peptide nanotube biomaterials are attractive for their range of applications. Herein, we disclose the co-assembly of coiled-coil peptides, one with ligands for metal ions that demonstrate hierarchical assembly into nanotubes, with spatial control of the… read more here.
Keywords: coil peptide; enhanced stability; coiled coil; metal dependent ... See more keywords
Recent advances in coiled-coil peptide materials and their biomedical applications.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04434j
Abstract: Extensive research has gone into deciphering the sequence requirements for peptides to fold into coiled-coils of varying oligomeric states. More recently, additional signals have been introduced within coiled-coils to promote higher order assembly into biomaterials… read more here.
Keywords: coiled coil; biomedical applications; peptide materials; advances coiled ... See more keywords
Equipping Coiled-Coil Peptide Dimers With Furan Warheads Reveals Novel Cross-Link Partners
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2021.799706
Abstract: Using a coiled-coil peptide dimer as a model system to explore furan reactivity, we describe novel cross-link partners of furan warheads for site-specific cross-linking. We demonstrate that replacement of weak interhelical ionic contacts with a… read more here.
Keywords: cross link; coil peptide; cross; coiled coil ... See more keywords