Orientational Ambiguity in Septin Coiled Coils and its Structural Basis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2021.166889
Abstract: Septins are an example of subtle molecular recognition whereby different paralogues must correctly assemble into functional filaments important for essential cellular events such as cytokinesis. Most possess C-terminal domains capable of forming coiled coils which… read more here.
Keywords: coiled coils; orientational ambiguity; septin coiled; coiled coil ... See more keywords
Coiled Coils - A Model System for the 21st Century.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2016.10.007
Abstract: α-Helical coiled coils were described more than 60 years ago as simple, repetitive structures mediating oligomerization and mechanical stability. Over the past 20 years, however, they have emerged as one of the most diverse protein… read more here.
Keywords: coiled coils; model system; 21st century; system 21st ... See more keywords
Prerequisites for Stabilizing Long-Range Synergistic Interactions among b-, c-, and f-Residues in Coiled Coils.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.1c00760
Abstract: Coiled coils are among the most abundant tertiary and quaternary structures found in proteins. A growing body of evidence suggests that long-range synergistic interactions among solvent-exposed residues can contribute substantially to coiled-coil conformational stability, but… read more here.
Keywords: coiled coils; long range; range synergistic; synergistic interactions ... See more keywords
Combinatorial use of disulfide bridges and native sulfur-SAD phasing for rapid structure determination of coiled-coils
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20181073
Abstract: Coiled-coils are ubiquitous protein–protein interaction motifs found in many eukaryotic proteins. The elongated, flexible and often irregular nature of coiled-coils together with their tendency to form fibrous arrangements in crystals imposes challenges on solving the… read more here.
Keywords: sulfur sad; coiled coils; sad phasing; combinatorial use ... See more keywords
Predicting substitutions to modulate disorder and stability in coiled-coils
Sign Up to like & getrecommendations! Published in 2020 at "BMC Bioinformatics"
DOI: 10.1186/s12859-020-03867-x
Abstract: Background Coiled-coils are described as stable structural motifs, where two or more helices wind around each other. However, coiled-coils are associated with local mobility and intrinsic disorder. Intrinsically disordered regions in proteins are characterized by… read more here.
Keywords: stability coiled; coiled coils; extent disorder; disorder ... See more keywords
Prediction of Protein–Protein Binding Interactions in Dimeric Coiled Coils by Information Contained in Folding Energy Landscapes
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22031368
Abstract: Coiled coils represent the simplest form of a complex formed between two interacting protein partners. Their extensive study has led to the development of various methods aimed towards the investigation and design of complex forming… read more here.
Keywords: protein; information contained; energy landscapes; coiled coils ... See more keywords