HBcAb seropositivity is correlated with poor HIV viremia control in an Italian cohort of HIV/HBV-coinfected patients on first-line therapy
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DOI: 10.1038/s41598-019-46976-1
Abstract: The morbidity and mortality rates of human immunodeficiency virus (HIV)-hepatitis B virus (HBV) coinfection are higher than that of either infection alone. Outcomes and the virological response to antiretrovirals (combination antiretroviral therapy, cART) were explored… read more here.
Keywords: hiv hbv; hiv; hiv viremia; coinfected patients ... See more keywords
Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR
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DOI: 10.1038/s41598-019-48592-5
Abstract: The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who achieved… read more here.
Keywords: hcv antibodies; hcv; hiv hcv; neutralizing anti ... See more keywords
Comparison of methods and characterization of small RNAs from plasma extracellular vesicles of HIV/HCV coinfected patients
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DOI: 10.1038/s41598-020-67935-1
Abstract: Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) hijack the host exosomal machinery as an additional mechanism of infection and evasion of the immune system, modifying the small RNA (smRNA) cargo during infection. We… read more here.
Keywords: extracellular vesicles; hiv hcv; phenol based; isolation ... See more keywords
High Treatment Uptake in Human Immunodeficiency Virus/Hepatitis C Virus–Coinfected Patients After Unrestricted Access to Direct-Acting Antivirals in the Netherlands
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DOI: 10.1093/cid/cix1004
Abstract: Background The Netherlands has provided unrestricted access to direct-acting antivirals (DAAs) since November 2015. We analyzed the nationwide hepatitis C virus (HCV) treatment uptake among patients coinfected with human immunodeficiency virus (HIV) and HCV. Methods… read more here.
Keywords: unrestricted access; treatment; hcv; treatment uptake ... See more keywords
Anti-TB drug concentrations and drug-associated toxicities among TB/HIV-coinfected patients
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DOI: 10.1093/jac/dkw534
Abstract: Background Toxicities due to anti-TB treatment frequently occur among TB/HIV-coinfected patients. Objectives To determine the association between anti-TB drug concentrations and the occurrence of hepatotoxicity and peripheral neuropathy among TB/HIV-coinfected patients. Methods TB/HIV-coinfected patients were… read more here.
Keywords: among hiv; drug; hiv coinfected; hepatotoxicity ... See more keywords
Sustained virologic response and changes in liver fibrosis parameters following 12-wk administration of generic sofosbuvir and daclatasvir in HIV/HCV-coinfected patients with HCV genotype 4 infection.
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DOI: 10.1093/trstmh/trz120
Abstract: BACKGROUND Novel direct-acting antiviral agents have shown great efficacy and tolerability in HCV-monoinfected patients. However, data are lacking regarding their efficacy and safety in HIV/HCV-genotype (GT) 4-coinfected patients. METHODS A single-centre, prospective study including HIV/HCV-GT… read more here.
Keywords: fibrosis; hcv; hiv hcv; hcv coinfected ... See more keywords
Interferon-free therapy for treating hepatitis C virus in difficult-to-treat HIV-coinfected patients
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DOI: 10.1097/qad.0000000000001699
Abstract: Background/aims: Data regarding the use of all-oral direct-acting antivirals in HIV/hepatitis C virus (HCV)-coinfected patients with advanced liver fibrosis are required, because they are generally under-represented in clinical trials. This study sought to evaluate the… read more here.
Keywords: use; treatment; hepatitis virus; adverse events ... See more keywords
Sofosbuvir-Based Regimens in HIV/HCV Coinfected Patients After Liver Transplantation: Results From the ANRS CO23 CUPILT Study
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DOI: 10.1097/tp.0000000000001928
Abstract: Background A recurrence of hepatitis C virus (HCV) after liver transplantation affects survival in human immunodeficiency virus (HIV)/HCV coinfected patients. This study assessed the efficacy and safety of sofosbuvir (SOF)-based regimens in HIV/HCV coinfected patients… read more here.
Keywords: hiv hcv; liver transplantation; transplantation; hcv coinfected ... See more keywords
Week 96 Results of Switching from Tenofovir Disoproxil Fumarate-Based Antiretroviral Therapy to Coformulated Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide among HIV/Hepatitis B Virus-Coinfected Patients
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DOI: 10.1128/spectrum.05125-22
Abstract: Elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide as a maintenance therapy showed durable and high rates of viral suppression for HIV/HBV-coinfected patients, with only 5.1% and 2.2% of patients having HBV DNA of ≥20 IU/mL and HIV RNA of ≥50 copies/mL,… read more here.
Keywords: hiv hbv; elvitegravir cobicistat; cobicistat emtricitabine; coinfected patients ... See more keywords
Meglumine antimoniate combination treatment for relapsing Kala-azar after treatment and secondary prophylaxis failure with liposomal amphotericin B in two HIV-coinfected patients
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DOI: 10.1136/bcr-2019-231929
Abstract: Visceral leishmaniasis (VL) is a protozoan infection caused by Leishmania infantum and L. donovani with a higher incidence and severity in HIV-infected patients due to its synergistic effect on hampering the immune response, often leading… read more here.
Keywords: treatment; liposomal amphotericin; hiv; prophylaxis ... See more keywords
Phylogenetic Diversity in Core Region of Hepatitis C Virus Genotype 1a as a Factor Associated with Fibrosis Severity in HIV-1-Coinfected Patients
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DOI: 10.1155/2017/1728456
Abstract: High hepatitis C virus (HCV) genetic diversity impacts infectivity/pathogenicity, influencing chronic liver disease progression associated with fibrosis degrees and hepatocellular carcinoma. HCV core protein is crucial in cell-growth regulation and host-gene expression. Liver fibrosis is… read more here.
Keywords: fibrosis; hcv; hiv coinfected; virus ... See more keywords