Severe cartilage degeneration in patients with developmental dysplasia of the hip
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1606
Abstract: Developmental dysplasia of the hip (DDH) is a developmental disorder that has long‐term chronic pain and limited hip joint mobility as major pathological characteristics. This study aims to access the association between the development of… read more here.
Keywords: hip; ddh patients; col; cartilage ... See more keywords
Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells—in vitro and ex vivo study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22487
Abstract: Colchicine (COL) shows strong anticancer activity but due to its toxicity towards normal cells its wider application is limited. To address this issue, a library of 17 novel COL derivatives, namely N‐carbamates of N‐deacetyl‐4‐(bromo/chloro/iodo)thiocolchicine, has… read more here.
Keywords: towards primary; breast; breast cancer; cancer cells ... See more keywords
Activation of PERK in ET‐1‐ and thrombin‐induced pulmonary fibroblast differentiation: Inhibitory effects of curcumin
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28256
Abstract: In the present study, we investigated the role of PKR‐like endoplasmic reticular kinase (PERK), an endoplasmic reticulum (ER) stress kinase, in endothelin 1 (ET‐1)‐ and thrombin‐induced pulmonary fibrosis (PF), and the preventive effects of curcumin… read more here.
Keywords: kinase; perk; differentiation; col ... See more keywords
Raman microspectroscopy/micro-optical coherence tomography approach for chairside diagnosis of periodontal diseases - A pilot study.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontology"
DOI: 10.1002/jper.21-0710
Abstract: BACKGROUND Our objective was to develop and test a combined Raman microspectroscopy (RMS) and micro-optical coherence tomography (μOCT) approach for chairside quantification of gingival collagen, DNA, epithelium and connective tissue. We hypothesized that a high-resolution… read more here.
Keywords: raman microspectroscopy; dna; col; rms oct ... See more keywords
Novel tubular constructs for urinary diversion: a biocompatibility study in pigs
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2122
Abstract: The use of bowel tissue for urinary diversion can be associated with severe complications, and regenerative medicine may circumvent this by providing an engineered conduit. In this study, a novel tubular construct was identified for… read more here.
Keywords: medicine; biocompatibility; urinary diversion; col ... See more keywords
Influence of electron beam irradiation doses on bone regeneration by octacalcium phosphate collagen composites
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2505
Abstract: An octacalcium phosphate and collagen composite (OCP/Col) achieved efficient bone regeneration with excellent resorbability. After the confirmation of its safety and efficacy in preclinical animal studies, the present study investigated the influence of electron beam… read more here.
Keywords: beam irradiation; bone; ocp col; col ... See more keywords
Complete mid-portion rupture of the rat achilles tendon leads to remote and time-mismatched changes in uninjured regions
Sign Up to like & getrecommendations! Published in 2020 at "Knee Surgery, Sports Traumatology, Arthroscopy"
DOI: 10.1007/s00167-020-06239-3
Abstract: Purpose To examine healing adaptations over 17 weeks post Achilles tendon (AT) rupture in the injured region (IR) compared to an uninjured region (UIR) of the AT. Methods Twenty-four rats were subjected to a complete right-sided… read more here.
Keywords: collagen; week; rupture; time ... See more keywords
Photobiomodulation with single and combination laser wavelengths on bone marrow mesenchymal stem cells: proliferation and differentiation to bone or cartilage
Sign Up to like & getrecommendations! Published in 2018 at "Lasers in Medical Science"
DOI: 10.1007/s10103-018-2620-8
Abstract: Tissue engineering aims to take advantage of the ability of undifferentiated stem cells to differentiate into multiple cell types to repair damaged tissue. Photobiomodulation uses either lasers or light-emitting diodes to promote stem cell proliferation… read more here.
Keywords: proliferation; bone; differentiation; col ... See more keywords
Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking
Sign Up to like & getrecommendations! Published in 2021 at "Angiogenesis"
DOI: 10.1007/s10456-021-09791-9
Abstract: Collagen type IV (Col IV) is a basement membrane protein associated with early blood vessel morphogenesis and is essential for blood vessel stability. Defects in vascular Col IV deposition are the basis of heritable disorders,… read more here.
Keywords: col; basement membrane; secretion; blood vessel ... See more keywords
A comprehensive calorimetric, spectroscopic, and molecular docking investigation to probe the interaction of colchicine with HEWL
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thermal Analysis and Calorimetry"
DOI: 10.1007/s10973-018-7800-z
Abstract: Colchicine (Col), a naturally occurring alkaloid, has been used as an anti-inflammatory, anti-fibrotic, and anti-tumor drug. The present study reports in vitro interaction between Col and hen egg white lysozyme (HEWL) by spectroscopy, isothermal titration… read more here.
Keywords: colchicine; hewl; spectroscopy; interaction ... See more keywords
Characterization of Tendon-Specific Markers in Various Human Tissues, Tenocytes and Mesenchymal Stem Cells
Sign Up to like & getrecommendations! Published in 2019 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-019-00182-2
Abstract: Background:Unlike bone, cartilage, or muscle, tendon-specific markers are not well established. The purpose of the study was to investigate expression pattern and level of 6 well-known tendon-specific markers, in various human musculoskeletal tissues, tenocytes, and… read more here.
Keywords: specific markers; tendon tissue; tendon specific; col ... See more keywords