Collagen type XII is undetectable in keratoconus Bowman’s layer
Sign Up to like & getrecommendations! Published in 2023 at "British Journal of Ophthalmology"
DOI: 10.1136/bjo-2022-322180
Abstract: Purpose Corneal biomechanical failure is the hallmark of keratoconus (KC); however, the cause of this failure remains elusive. Collagen type XII (COL12A1), which localises to Bowman’s layer (BL), is thought to function in stress-bearing areas,… read more here.
Keywords: type xii; collagen type; col12a1; keratoconus ... See more keywords
COL12A1 as a prognostic biomarker links immunotherapy response in breast cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine-related cancer"
DOI: 10.1530/erc-23-0012
Abstract: Immunotherapy has shown promising efficacy for breast cancer (BC) patients. Yet the predictive biomarkers for immunotherapy response remains lacking. Based on two GEO datasets, 53 differentially expressed genes (DEGs) associated with durvalumab treatment response, were… read more here.
Keywords: breast cancer; response; col12a1; immunotherapy response ... See more keywords
COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation
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DOI: 10.3390/cancers15051480
Abstract: Simple Summary Cancer-associated fibroblasts (CAFs) are key stromal cells in the tumor microenvironment (TME) that play a crucial role in tumor progression in pancreatic cancer. Thus, uncovering the key genes involved in CAF progression and… read more here.
Keywords: pancreatic cancer; expression; cancer associated; tumor ... See more keywords
METTL3 Facilitates Tumor Progression by COL12A1/MAPK Signaling Pathway in Esophageal Squamous Cell Carcinoma
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DOI: 10.7150/jca.66830
Abstract: Background: Esophageal squamous cell carcinoma (ESCC) is one of the most common aggressive tumors in the world. m6A modification has been implicated to play an important role in many biological progressions. METTL3 as the main… read more here.
Keywords: cell; progression; expression; esophageal squamous ... See more keywords