Spatial-reprogramming derived GPNMB+ macrophages interact with COL6A3+ fibroblasts to enhance vascular fibrosis in glioblastoma
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DOI: 10.1186/s13073-025-01553-2
Abstract: Neoadjuvant therapy plays an important role in the treatment of glioblastoma (GBM), but a considerable proportion of patients remain unresponsive to the combination of immune checkpoint blockade (ICB) and antiangiogenic therapy. Understanding the mechanisms underlying… read more here.
Keywords: col6a3 tafs; spatial reprogramming; glioblastoma; vascular fibrosis ... See more keywords