Defining colchicine resistance/intolerance in patients with familial Mediterranean fever: a modified-Delphi consensus approach.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/keaa863
Abstract: OBJECTIVES Colchicine is the main treatment for familial Mediterranean fever (FMF). Although a number of individuals with FMF are intolerant/resistant to colchicine, there is no standard definition of colchicine resistance/intolerance. We developed a set of… read more here.
Keywords: colchicine resistance; intolerance; resistance; defining colchicine ... See more keywords
A score for predicting colchicine resistance at the time of diagnosis in familial Mediterranean fever: data from the TURPAID registry.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead242
Abstract: OBJECTIVES Colchicine forms the mainstay of treatment in familial Mediterranean fever (FMF). Around 5-10% of FMF patients are colchicine resistant and require anti-interleukin-1 drugs. We aimed to compare the characteristics of colchicine-resistant and colchicine-responsive patients… read more here.
Keywords: diagnosis; colchicine resistant; colchicine; colchicine resistance ... See more keywords
Colchicine resistance: Associated factors and its effect on health‐related quality of life in patients with familial Mediterranean fever
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14407
Abstract: To determine the factors associated with colchicine resistance and the effect of colchicine resistance on health‐related quality of life (QoL) in patients with familial Mediterranean fever (FMF). read more here.
Keywords: colchicine resistance; resistance; patients familial; quality life ... See more keywords
In silico study of colchicine resistance molecular mechanisms caused by tubulin structural polymorphism
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DOI: 10.1371/journal.pone.0221532
Abstract: Starting from 1972, colchicine is known as the most useful drug for prevention of familial Mediterranean fever attacks. However, some patients do not respond to colchicine treatment, even taken in high doses. Despite the fact,… read more here.
Keywords: colchicine resistance; amino acid; colchicine; molecular mechanisms ... See more keywords