Recipes for Inducing Cold Denaturation in an Otherwise Stable Protein.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c13355
Abstract: Although cold denaturation is a fundamental phenomenon common to all proteins, it can only be observed in a handful of cases where it occurs at temperatures above the freezing point of water. Understanding the mechanisms… read more here.
Keywords: denaturation; stable protein; cold denaturation; denaturation otherwise ... See more keywords
Heightened Cold-Denaturation of Proteins at the Ice-Water Interface.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b13454
Abstract: The process of freezing proteins is widely used in applications ranging from processing and storage of biopharmaceuticals to Cryo-EM analysis of protein complexes. The formation of an ice-water interface is a critical destabilization factor for… read more here.
Keywords: protein; water interface; ice water; water ... See more keywords
Applying text mining to identify relevant literature in food science: Cold denaturation as a case study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of food science"
DOI: 10.1111/1750-3841.15940
Abstract: In a research environment characterized by the five V's of big data, volume, velocity, variety, value, and veracity, the need to develop tools that quickly screen a large number of publications into relevant work is… read more here.
Keywords: research; literature; field; cold denaturation ... See more keywords
Salt-Specific Suppression of the Cold Denaturation of Thermophilic Multidomain Initiation Factor 2
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DOI: 10.3390/ijms24076787
Abstract: Thermophilic proteins and enzymes are attractive for use in industrial applications due to their resistance against heat and denaturants. Here, we report on a thermophilic protein that is stable at high temperatures (Ttrs, hot 67… read more here.
Keywords: initiation factor; denaturation thermophilic; cold denaturation; thermophilic multidomain ... See more keywords